{"id":"W4322623890","doi":"10.1021/acs.est.2c08463","title":"Acute Exposure of Zebrafish (<i>Danio rerio</i>) to the Next-Generation Perfluoroalkyl Substance, Perfluoroethylcyclohexanesulfonate, Shows Similar Effects as Legacy Substances","year":2023,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Per- and polyfluoroalkyl substances research","field":"Environmental Science","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Global Institute for Water Security; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Baylor University","keywords":"Danio; Zebrafish; Potency; Pharmacology; Environmental chemistry; Toxicology; In vivo; Chemistry; Biology; In vitro; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001052137,0.000375894,0.0001909382,0.0001478813,0.0001898133,0.0001769126,0.0001369238,0.0003966001,0.001510762],"category_scores_gemma":[0.0001164357,0.0001215512,0.0003933734,0.00007907671,0.0002491544,0.0001656861,0.0001955568,0.0004001182,0.0002680166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004594364,"about_ca_system_score_gemma":0.0003395941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006048697,"about_ca_topic_score_gemma":0.01299118,"domain_scores_codex":[0.9998615,0.00001233155,0.00001237371,0.00004179529,0.00004398557,0.00002800272],"domain_scores_gemma":[0.9999037,0.00001071001,0.0000354928,0.000009673146,0.00002504682,0.0000153705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001063487,0.00002084479,0.001262266,0.00004321151,0.00001193543,0.00007847064,0.00002103249,0.00006311887,0.9970771,0.00002314411,0.0001015305,0.001191024],"study_design_scores_gemma":[0.00001181939,0.002147984,0.02603216,0.00001744037,0.00004815327,0.0001850361,0.00009949701,0.0002927164,0.9684614,0.00004806325,0.002640777,0.0000149758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937814,0.0008325737,0.001288324,0.0001836703,0.00005448474,0.00003781679,0.0007964273,0.00006162823,0.002963559],"genre_scores_gemma":[0.9888303,0.001052102,0.00179565,0.0002508739,0.000009624586,0.00006669678,0.00106912,0.00001656695,0.006909091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006048697,"threshold_uncertainty_score":0.01202703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01777707299115489,"score_gpt":0.2551418768910204,"score_spread":0.2373648038998655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}