{"id":"W4322628560","doi":"10.3390/v15030646","title":"Manganese Mediates Its Antiviral Functions in a cGAS-STING Pathway Independent Manner","year":2023,"lang":"en","type":"article","venue":"Viruses","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Saskatchewan","funders":"Higher Education Discipline Innovation Project; Priority Academic Program Development of Jiangsu Higher Education Institutions; National Natural Science Foundation of China","keywords":"Sting; Innate immune system; Biology; DNA virus; Virus; CRISPR; RNA interference; Virology; Immune system; RNA; Cell biology; Gene; Immunology; Genetics; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003187743,0.0001593135,0.0002128534,0.0003975449,0.0001434451,0.00002145459,0.0001699142,0.0001822599,0.0007286376],"category_scores_gemma":[0.0002707232,0.0001356804,0.00006894145,0.0003575156,0.00007848426,0.0001619472,0.0001408058,0.0002950767,0.01198247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000311294,"about_ca_system_score_gemma":0.0000463765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001523225,"about_ca_topic_score_gemma":0.0001700841,"domain_scores_codex":[0.998791,0.0002333851,0.00026362,0.0002516512,0.00004136199,0.0004189909],"domain_scores_gemma":[0.9994494,0.0002587959,0.00005956925,0.0001852098,0.00003365399,0.00001333648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002701954,0.00009806445,0.02428763,0.00001735882,0.00007070944,0.00007086005,0.0006783302,0.000007950008,0.9664372,0.0004968732,0.005280877,0.002283939],"study_design_scores_gemma":[0.001382554,0.0002235613,0.1660439,0.0001057544,0.00001802238,0.00005244577,0.002249154,0.00001779958,0.7282838,0.00005991009,0.101211,0.0003521225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944355,0.001539765,0.000003330126,0.0001518313,0.001189393,0.000154128,0.00006263906,0.0002386323,0.00222478],"genre_scores_gemma":[0.985705,0.0001032249,0.000002651612,0.0002493781,0.00003982411,0.00004839879,0.0000755443,0.00002169051,0.01375428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2381534,"threshold_uncertainty_score":0.9887868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03465677997837074,"score_gpt":0.2748210505272927,"score_spread":0.2401642705489219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}