{"id":"W4322628560","doi":"10.3390/v15030646","title":"Manganese Mediates Its Antiviral Functions in a cGAS-STING Pathway Independent Manner","year":2023,"lang":"en","type":"article","venue":"Viruses","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Saskatchewan","funders":"Higher Education Discipline Innovation Project; Priority Academic Program Development of Jiangsu Higher Education Institutions; National Natural Science Foundation of China","keywords":"Sting; Innate immune system; Biology; DNA virus; Virus; CRISPR; RNA interference; Virology; Immune system; RNA; Cell biology; Gene; Immunology; Genetics; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323386,0.0004043587,0.0002271466,0.0001366514,0.0001490286,0.0003427655,0.0002104807,0.000255155,0.001101725],"category_scores_gemma":[0.00007806606,0.00008012245,0.000275113,0.00007407228,0.0002299073,0.0002271891,0.0002749166,0.0003646161,0.0002224081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003621997,"about_ca_system_score_gemma":0.0002653292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007287244,"about_ca_topic_score_gemma":0.001456164,"domain_scores_codex":[0.9998746,0.00002415085,0.000007955483,0.00003234112,0.00003041017,0.00003050977],"domain_scores_gemma":[0.9999505,0.000005509276,0.00001527915,0.000007276024,0.000009504624,0.00001184409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001122738,0.00001407411,0.0001740584,0.0000624419,0.000007365678,0.00004411301,0.000008899901,0.00003690085,0.9981635,0.0001877576,0.00005867245,0.001129865],"study_design_scores_gemma":[0.00002424284,0.0002204926,0.003113922,0.00001229413,0.00002275726,0.0002100689,0.00003575975,0.001074004,0.9891247,0.0001491462,0.006006963,0.000005692468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741097,0.005328347,0.01189574,0.0003971288,0.0001681272,0.00006616283,0.0004856859,0.0002714593,0.00727771],"genre_scores_gemma":[0.9926363,0.001064636,0.001936625,0.00005995518,0.0000136013,0.00002376354,0.000214474,0.00001123219,0.004039365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001101725,"threshold_uncertainty_score":0.003685653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03465677997837074,"score_gpt":0.2748210505272927,"score_spread":0.2401642705489219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}