{"id":"W4322732084","doi":"10.1186/s12864-023-09174-y","title":"Amino acid substitutions in specific proteins correlate with farnesol unresponsiveness in Candida albicans","year":2023,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Université de Montréal; Ministère de l'Agriculture, des Pêcheries et de l'Alimentation; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Université Laval","keywords":"Farnesol; Biology; Candida albicans; Amino acid; Yeast; Corpus albicans; Biochemistry; Gene; Biofilm; Genetics; Microbiology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009406728,0.0003195665,0.0002051379,0.0005702662,0.0001722321,0.0002593538,0.000234847,0.0003846578,0.001467549],"category_scores_gemma":[0.0002449219,0.0001084373,0.000323368,0.0004246759,0.0002280592,0.0001223455,0.0001698199,0.0003803085,0.0002598081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001435056,"about_ca_system_score_gemma":0.00009865626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005190817,"about_ca_topic_score_gemma":0.0003582653,"domain_scores_codex":[0.9998647,0.00001117517,0.00002071116,0.00003776234,0.00004001429,0.00002560535],"domain_scores_gemma":[0.9996512,0.000052643,0.0001615215,0.00002524095,0.00004764002,0.00006179074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002545115,0.0000477482,0.009259189,0.00006022489,0.00002587302,0.0004977138,0.00003306138,0.0000415123,0.9884087,0.00001653104,0.00003783806,0.001317084],"study_design_scores_gemma":[0.0000180568,0.0005757753,0.5241188,0.00001784197,0.0001085068,0.006114973,0.0001847591,0.0006078124,0.4669575,0.0001058745,0.001167378,0.00002277989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987444,0.0004224585,0.000206537,0.00002315247,0.000007801847,0.000008163286,0.0002964373,0.00001499752,0.0002760255],"genre_scores_gemma":[0.9984226,0.0002338437,0.0004893591,0.00003415549,0.000006532093,0.00001085481,0.0005037492,0.00000727702,0.0002915724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001467549,"threshold_uncertainty_score":0.004909456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03459521202587283,"score_gpt":0.2700165768580642,"score_spread":0.2354213648321913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}