{"id":"W4322732173","doi":"10.1038/s41467-023-36612-y","title":"Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche; Institute of Genetics; Institute of Molecular and Cell Biology; Fondation pour la Recherche Médicale; University of Oxford","keywords":"Biology; Mesenchymal stem cell; Cell biology; Stromal cell; Haematopoiesis; Progenitor cell; Zebrafish; Stem cell; ALCAM; Cancer research; Genetics; Cell adhesion molecule","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003624625,0.00009132869,0.0001070757,0.00005759511,0.0003690395,0.00002258274,0.001158836,0.0001927104,0.00001203883],"category_scores_gemma":[0.0003900311,0.00007216963,0.0000601641,0.0002341212,0.0003530265,0.000003983027,0.001021306,0.0002131031,0.000008258071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001022892,"about_ca_system_score_gemma":0.000163688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002637456,"about_ca_topic_score_gemma":0.0001663866,"domain_scores_codex":[0.9991914,0.00004510421,0.0001889177,0.0001873817,0.0001911795,0.0001960093],"domain_scores_gemma":[0.9979786,0.0002879833,0.0001018442,0.001390808,0.0001593794,0.00008140343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003128927,0.0001142064,0.00112965,0.00005040088,0.000159418,1.50181e-7,0.0002040765,0.000001212143,0.9567247,0.0008115538,0.03773582,0.003037554],"study_design_scores_gemma":[0.0006388935,0.00005175452,0.06185134,0.00002201693,0.00003382005,0.000002165471,0.0008049071,0.0001602733,0.7085195,0.0001781497,0.2275758,0.0001614182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9702666,0.002099869,0.003595118,0.02070438,0.00011808,0.002136341,0.0004620454,0.00007332616,0.0005442646],"genre_scores_gemma":[0.986758,0.0009138834,0.01087746,0.0001115691,0.00003597074,0.000590689,0.0005354477,0.00001651385,0.0001604583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2482052,"threshold_uncertainty_score":0.2942992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03329617365451706,"score_gpt":0.3382228119240752,"score_spread":0.3049266382695581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}