{"id":"W4322771803","doi":"10.1158/1538-7445.sabcs22-p2-13-04","title":"Abstract P2-13-04: Inclusion of Patients with Leptomeningeal Disease in Phase III Randomized Clinical Trials of Patients with Advanced Breast Cancer, Lung Cancer, and Melanoma: A Systematic Review","year":2023,"lang":"en","type":"review","venue":"Cancer Research","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; McMaster University; University of Toronto; Health Sciences Centre; Alberta Health Services","funders":"","keywords":"Medicine; Breast cancer; Cancer; Lung cancer; Randomized controlled trial; Internal medicine; Population; Clinical trial; Asymptomatic; Oncology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0284367,0.002016702,0.01528766,0.006285111,0.0009608896,0.005202543,0.002763619,0.003528941,0.01093628],"category_scores_gemma":[0.1146476,0.001358331,0.01101639,0.00826933,0.001819657,0.004608054,0.001892848,0.001905977,0.0008600619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00677902,"about_ca_system_score_gemma":0.01142829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005329168,"about_ca_topic_score_gemma":0.01412057,"domain_scores_codex":[0.9582622,0.02021125,0.0149156,0.0019723,0.003913193,0.0007255141],"domain_scores_gemma":[0.9120952,0.06524708,0.01515932,0.001455923,0.00518921,0.0008532546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0005106491,0.00001044307,0.0005088873,0.9791393,0.01375629,0.00004991871,0.00008417121,0.00005756259,0.0001066048,0.0001551572,0.001004813,0.00461633],"study_design_scores_gemma":[0.003470481,0.0004388941,0.003531292,0.8274601,0.1548071,0.000209207,0.0002667647,0.0002492948,0.00029384,0.0006103399,0.008612794,0.00004992033],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006681085,0.9739203,0.001160077,0.00142437,0.0006630683,0.01062061,0.003731538,0.000131133,0.00166781],"genre_scores_gemma":[0.1732744,0.774464,0.006793657,0.006541731,0.0005837182,0.03388407,0.002806718,0.0001214271,0.00153033],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0284367,"threshold_uncertainty_score":0.1503895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1276042889883905,"score_gpt":0.5297660016737155,"score_spread":0.402161712685325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}