{"id":"W4322774773","doi":"10.1158/1538-7445.sabcs22-p4-01-42","title":"Abstract P4-01-42: Pooled analysis of post-progression treatments after first-line ribociclib + endocrine therapy in patients with HR+/HER2− advanced breast cancer in the MONALEESA-2, -3, and -7 studies","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Novartis (Canada)","funders":"","keywords":"Medicine; Internal medicine; Breast cancer; Oncology; Cancer; Propensity score matching; Adjuvant therapy; Targeted therapy; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01429794,0.001933949,0.0071904,0.002816268,0.0003068908,0.002120142,0.0009906607,0.001195822,0.003534778],"category_scores_gemma":[0.01780088,0.0007199007,0.03171002,0.003229103,0.0003915862,0.0009792374,0.001757579,0.001364109,0.000403891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000691938,"about_ca_system_score_gemma":0.0008743648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002092864,"about_ca_topic_score_gemma":0.003227477,"domain_scores_codex":[0.9845633,0.008924581,0.002694361,0.001885996,0.001460163,0.0004716232],"domain_scores_gemma":[0.9884172,0.006411833,0.003012953,0.0009774771,0.0008766436,0.0003038529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.03459975,0.0000537731,0.03486827,0.01651334,0.9024525,0.0001266039,0.00008271643,0.0008141469,0.0009996446,0.00009675346,0.001042824,0.008349671],"study_design_scores_gemma":[0.005313555,0.003393548,0.09379339,0.00170176,0.8894854,0.0002011886,0.0001550061,0.0006935558,0.0005435378,0.0002716164,0.004391782,0.00005563136],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4647959,0.4911342,0.006051409,0.0007641006,0.0007559864,0.001924969,0.0299804,0.0002597172,0.004333375],"genre_scores_gemma":[0.9739199,0.01601853,0.00152831,0.0004311622,0.0002000066,0.001457331,0.005408408,0.00006392154,0.0009723212],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01429794,"threshold_uncertainty_score":0.0756157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04679614256199177,"score_gpt":0.4301476894820493,"score_spread":0.3833515469200576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}