{"id":"W4322774773","doi":"10.1158/1538-7445.sabcs22-p4-01-42","title":"Abstract P4-01-42: Pooled analysis of post-progression treatments after first-line ribociclib + endocrine therapy in patients with HR+/HER2− advanced breast cancer in the MONALEESA-2, -3, and -7 studies","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Novartis (Canada)","funders":"","keywords":"Medicine; Internal medicine; Breast cancer; Oncology; Cancer; Propensity score matching; Adjuvant therapy; Targeted therapy; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005152065,0.0003184013,0.0007847037,0.001064542,0.0001178508,0.0000213054,0.0002220771,0.00006994952,0.0002827014],"category_scores_gemma":[0.00005896158,0.0001850964,0.0001022651,0.003791353,0.0004427245,0.000229502,0.0001119079,0.0004683739,0.000003692094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005554004,"about_ca_system_score_gemma":0.000185811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001615937,"about_ca_topic_score_gemma":0.007237524,"domain_scores_codex":[0.9968293,0.000167839,0.0004627538,0.0006166942,0.001187514,0.0007358955],"domain_scores_gemma":[0.9981487,0.0003891978,0.0001462297,0.0005019686,0.000693077,0.0001207743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01466914,0.0005363039,0.8062891,0.0001774525,0.00168766,0.0001140849,0.002904141,0.0008562667,0.001380257,0.000002967518,0.0000134675,0.1713692],"study_design_scores_gemma":[0.009656874,0.0007511919,0.9859512,0.0008842396,0.0002337935,0.000002446917,0.001287532,0.00006319381,0.0007849696,0.00004665316,0.0001642708,0.0001736446],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792744,0.01463235,7.534545e-7,0.004040351,0.00004391262,0.001471008,0.0004874163,0.00003163455,0.00001820966],"genre_scores_gemma":[0.9836672,0.01379016,0.00004271615,0.0001642471,0.00006562582,0.002007029,0.00008253346,0.00005207493,0.0001284041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1796621,"threshold_uncertainty_score":0.7548011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04679614256199177,"score_gpt":0.4301476894820493,"score_spread":0.3833515469200576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}