{"id":"W4322775453","doi":"10.1158/1538-7445.sabcs22-p6-04-02","title":"Abstract P6-04-02: Ki67 Assessment Protocol: Companion Diagnostic Biomarker for LUMINA Prospective Cohort Study","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto; University of British Columbia","funders":"","keywords":"Medicine; Breast cancer; Prospective cohort study; Protocol (science); Cancer; Radiation therapy; Biomarker; Oncology; Pathology; Internal medicine; Nuclear medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01801389,0.001210098,0.001243615,0.001394187,0.001542217,0.001794065,0.002447018,0.002744226,0.02426222],"category_scores_gemma":[0.02621814,0.00112656,0.0009403264,0.002008588,0.0006760934,0.00106189,0.001745997,0.001691518,0.0194844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001399009,"about_ca_system_score_gemma":0.004177816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00121848,"about_ca_topic_score_gemma":0.001824517,"domain_scores_codex":[0.9923599,0.004238817,0.001335564,0.0008876934,0.0008427652,0.0003352205],"domain_scores_gemma":[0.9830414,0.002209757,0.002137758,0.006434869,0.004715013,0.001461195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1403307,0.008363566,0.2449256,0.008294194,0.001675905,0.001728888,0.001930668,0.006341415,0.03031877,0.01223745,0.3959061,0.1479467],"study_design_scores_gemma":[0.03747294,0.0209078,0.4462394,0.002432258,0.0008312042,0.002029913,0.0004674842,0.009614898,0.01034728,0.004591351,0.4647081,0.0003573281],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.07219085,0.0007437509,0.0627059,0.001857237,0.001074076,0.692782,0.1429718,0.001717177,0.02395719],"genre_scores_gemma":[0.0561999,0.0002938831,0.04436211,0.001624866,0.0003386899,0.8211986,0.06862218,0.0002343065,0.007125374],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02426222,"threshold_uncertainty_score":0.09526771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07947251442612975,"score_gpt":0.4762279318745323,"score_spread":0.3967554174484026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}