{"id":"W4322775477","doi":"10.1158/1538-7445.sabcs22-pd5-03","title":"Abstract PD5-03: PD5-03 Comparison of a personalized sequencing assay and digital PCR for circulating tumor DNA based Molecular Residual Disease detection in early-stage triple negative breast cancer in the cTRAK-TN trial","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Digital polymerase chain reaction; Multiplex; Medicine; Circulating tumor DNA; Internal medicine; Minimal residual disease; Oncology; Breast cancer; Stage (stratigraphy); Cancer; Multiplex polymerase chain reaction; Polymerase chain reaction; Bioinformatics; Biology; Genetics; Leukemia; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005279468,0.000581092,0.000874539,0.000165296,0.0001478053,0.001029746,0.0007859875,0.0007697248,0.004548475],"category_scores_gemma":[0.003457376,0.0002597054,0.0008900312,0.0002399617,0.0004761047,0.0007455848,0.0004306267,0.00151915,0.0005845616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009422913,"about_ca_system_score_gemma":0.0006638799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006227906,"about_ca_topic_score_gemma":0.0007757975,"domain_scores_codex":[0.9974744,0.001603432,0.0001731187,0.0004012423,0.000243544,0.0001042787],"domain_scores_gemma":[0.997938,0.000686601,0.0005111505,0.0002752563,0.0002056355,0.0003833181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.9274147,0.00190017,0.01272486,0.0004654033,0.001166936,0.00003148431,0.00005332402,0.001551631,0.00807776,0.0002373119,0.001976524,0.04439978],"study_design_scores_gemma":[0.4342905,0.4310268,0.09536821,0.0001699995,0.005612283,0.0004670015,0.0001180647,0.01440165,0.01011384,0.0009036093,0.007401333,0.0001267433],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911575,0.002062569,0.001042097,0.000324721,0.0001446159,0.0006745882,0.001237498,0.00007458147,0.003281913],"genre_scores_gemma":[0.9956322,0.0001930155,0.0009246269,0.000351334,0.00007664807,0.000451175,0.001303838,0.00001302472,0.001054084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005279468,"threshold_uncertainty_score":0.02792084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06724700861028891,"score_gpt":0.3810912684185115,"score_spread":0.3138442598082226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}