{"id":"W4323035491","doi":"10.1139/cjpp-2022-0428","title":"Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1<i>H</i>-pyrazol-4-yl)-1<i>H</i>-tetrazole: role of NO/cGMP pathway and calcium channels","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pharmacology; Chemistry; Licking; Nociception; Tetrazole; Phenylephrine; Carrageenan; Anesthesia; Medicine; Stereochemistry; Receptor; Biochemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002304775,0.0002538628,0.0006338559,0.0002121307,0.0001409846,0.00001258022,0.0001740683,0.0002426538,0.00005659676],"category_scores_gemma":[0.00005032624,0.0002236901,0.000111885,0.0001289102,0.0006218136,0.00002347104,0.00008221615,0.0002164276,0.000001877929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008394017,"about_ca_system_score_gemma":0.0004384946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003919792,"about_ca_topic_score_gemma":0.0001001755,"domain_scores_codex":[0.9986777,0.0001180739,0.0004357232,0.0002751258,0.00008303647,0.0004103075],"domain_scores_gemma":[0.9987679,0.0001425129,0.0003898129,0.0001215773,0.0001717909,0.0004064805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001396741,0.00003496621,0.005784727,0.0003548247,0.0002626765,0.00003455707,0.0004494711,0.00002483601,0.9890891,0.0001068194,0.001871989,0.001846309],"study_design_scores_gemma":[0.001497218,0.0006898657,0.03316465,0.00007818503,0.0001223508,0.0001098792,0.0002159766,0.00009560106,0.9513571,0.0005899847,0.01183604,0.0002431543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923455,0.006433262,0.00001398255,0.0001560684,0.0007383974,0.0001544123,0.00006241943,0.000004702401,0.00009130104],"genre_scores_gemma":[0.9969565,0.002088253,0.00005280825,0.0002158105,0.0005493028,0.000004271407,0.00001500981,0.00002416893,0.00009387451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03773206,"threshold_uncertainty_score":0.912182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008232394786165465,"score_gpt":0.2302114908781349,"score_spread":0.2219790960919694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}