{"id":"W4323052220","doi":"10.1101/2023.02.28.530488","title":"Predicting developmental relationships of tumor resident and circulating T cells in ovarian cancer","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"CD8; Biology; Ovarian cancer; Cytotoxic T cell; Effector; T cell; Immune system; Cancer research; Cell biology; T-cell receptor; Immunology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001531925,0.00008137836,0.0001380463,0.0004182871,0.00008653026,0.0003044966,0.00009719351,0.0001798103,0.0005955614],"category_scores_gemma":[0.0003631846,0.00008839315,0.00005529839,0.0002699188,0.00006797782,0.0001440491,0.0001187453,0.0001806121,0.0001305651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002428095,"about_ca_system_score_gemma":0.0001349111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001352582,"about_ca_topic_score_gemma":0.001799696,"domain_scores_codex":[0.9999501,0.000008736864,0.000002578719,0.00001765191,0.00000955804,0.00001140319],"domain_scores_gemma":[0.9998953,0.00003847388,0.00002593955,0.000005192052,0.00001555768,0.00001935383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00111637,0.00005686832,0.5373198,0.00009931091,0.00002882762,0.0002651619,0.0001604908,0.004575895,0.4096702,0.0003813983,0.0003723593,0.04595349],"study_design_scores_gemma":[0.00003051867,0.0003263435,0.8067084,0.00001922352,0.00005410505,0.001066941,0.0005932663,0.05411788,0.1328129,0.0008542989,0.003405487,0.00001072991],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960878,0.0004725448,0.002733893,0.00001896282,0.000002439834,0.000007748128,0.0002636432,0.00002608194,0.0003868656],"genre_scores_gemma":[0.9972695,0.000160733,0.001936028,0.000009328949,0.000003536446,0.00001118218,0.0002966464,0.000005016792,0.0003080007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001352582,"threshold_uncertainty_score":0.002689481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02761136325470366,"score_gpt":0.2277045389933845,"score_spread":0.2000931757386809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}