{"id":"W4323294018","doi":"10.1128/aac.01525-22","title":"Antimicrobial Activity of Gepotidacin Tested against Escherichia coli and Staphylococcus saprophyticus Isolates Causing Urinary Tract Infections in Medical Centers Worldwide (2019 to 2020)","year":2023,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Urinary Tract Infections Management","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biomedical Advanced Research and Development Authority; Medical Center, University of Rochester; Allergan; National Institutes of Health; Shionogi; Astellas Pharma; North Bristol NHS Trust; University of Queensland; bioMérieux; Amplyx; University of North Texas; National University of Singapore; Université de Sherbrooke; Medpace; University of Rochester; GlaxoSmithKline; Cidara Therapeutics; Tufts Medical Center; Nabriva Therapeutics; Wayne State University; Meiji Seika Pharma; Pfizer","keywords":"Staphylococcus saprophyticus; Urinary system; Microbiology; Antimicrobial; Escherichia coli; Medicine; Staphylococcus aureus; Staphylococcus; Biology; Internal medicine; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003868109,0.000329094,0.0003231936,0.000509937,0.0001048112,0.0002420142,0.0002143639,0.0003129015,0.0007188404],"category_scores_gemma":[0.0008367646,0.0001430413,0.0002326649,0.0006237841,0.0001664824,0.0003050312,0.0002827408,0.0002263935,0.0001097472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000218722,"about_ca_system_score_gemma":0.0002100971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00186544,"about_ca_topic_score_gemma":0.003636737,"domain_scores_codex":[0.9994678,0.0001188385,0.00008420295,0.0001233925,0.0001558163,0.00004993515],"domain_scores_gemma":[0.9994004,0.0001141281,0.0001996902,0.00002433931,0.0001626814,0.00009886577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004874929,0.001033546,0.345054,0.000597855,0.0003068632,0.0005144073,0.0003463147,0.001000198,0.6062536,0.00005059108,0.0003194775,0.03964829],"study_design_scores_gemma":[0.0001926405,0.02148733,0.8431652,0.00004527272,0.0002361891,0.002517532,0.0002990383,0.0009957892,0.1283788,0.00002663191,0.002621571,0.00003386572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986803,0.0005176402,0.000071209,0.00001815477,0.000004015238,0.00001384901,0.0003354256,0.000004599026,0.0003547939],"genre_scores_gemma":[0.997813,0.0004131518,0.0004476123,0.00003172151,0.000006784531,0.00001364777,0.001047692,0.000001666481,0.0002246407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00186544,"threshold_uncertainty_score":0.003709197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01140255023564004,"score_gpt":0.2703985604463942,"score_spread":0.2589960102107542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}