{"id":"W4323314444","doi":"10.3390/ijms24054916","title":"The Potential Role of MiRs-139-5p and -454-3p in Endoglin-Knockdown-Induced Angiogenic Dysfunction in HUVECs","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Vascular Anomalies and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institutes of Health; National Institute of Neurological Disorders and Stroke; University of Toronto","keywords":"Gene knockdown; Angiogenesis; microRNA; Biology; Cancer research; Endoglin; Umbilical vein; Microarray analysis techniques; Cell biology; Genetics; Apoptosis; Gene; Gene expression; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002827834,0.0003605277,0.0004014554,0.0001925423,0.0001856044,0.0003762519,0.0001733492,0.0002679898,0.0006106683],"category_scores_gemma":[0.0002883306,0.0002041019,0.0003322136,0.000123398,0.000258686,0.0001985292,0.0002115831,0.0004834143,0.0002964298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002385774,"about_ca_system_score_gemma":0.0002774357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005971802,"about_ca_topic_score_gemma":0.0006620415,"domain_scores_codex":[0.9996744,0.00004805784,0.00003871475,0.00009310829,0.0001030379,0.00004261003],"domain_scores_gemma":[0.9998629,0.00003301656,0.00003884092,0.00001497248,0.00003061361,0.00001956247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000116449,0.00001753943,0.0004400072,0.00005371904,0.0000105462,0.00005624994,0.00002752689,0.00008048233,0.9976912,0.0001071506,0.00004874382,0.001350364],"study_design_scores_gemma":[0.000008482146,0.0001247461,0.004225245,0.000005190622,0.00003025318,0.0001113029,0.00001843251,0.001135076,0.9926415,0.00005207573,0.001642964,0.000004581289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824071,0.003123409,0.01060414,0.0001987516,0.0001243697,0.00005615031,0.001144914,0.0002198831,0.002121402],"genre_scores_gemma":[0.9865268,0.001270505,0.008517134,0.000205733,0.00001598874,0.0001366632,0.00129832,0.00006756087,0.001961227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006106683,"threshold_uncertainty_score":0.002042949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01154106942520948,"score_gpt":0.278192152070152,"score_spread":0.2666510826449425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}