{"id":"W4323342633","doi":"10.1007/978-3-031-22468-3_7","title":"Healthy Brain Ageing and Longevity; the Harmony of Natural Products, APOE Polymorphism, and Melatonin","year":2023,"lang":"en","type":"book-chapter","venue":"Healthy ageing and longevity","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Melatonin; Longevity; Ageing; Neuroprotection; Apolipoprotein E; Biology; Alzheimer's disease; Healthy ageing; Internal medicine; Endocrinology; Disease; Medicine; Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001781216,0.0002960071,0.0003341594,0.0004078716,0.0001849524,0.0008518439,0.0002875959,0.0005796056,0.007650246],"category_scores_gemma":[0.0002797142,0.00009010288,0.0001469226,0.0005413474,0.0003631604,0.0007109603,0.0002735156,0.0007629956,0.001191661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000356109,"about_ca_system_score_gemma":0.0003373446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001620291,"about_ca_topic_score_gemma":0.005974567,"domain_scores_codex":[0.9999665,0.000008481599,0.000001931871,0.000006497358,0.00001380144,0.000002750286],"domain_scores_gemma":[0.9999363,0.00004332633,0.000004599974,0.000001998053,0.000007375946,0.000006280538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002440401,0.0001056753,0.001145323,0.0009895583,0.00004722498,0.0005686936,0.0004546102,0.0004012654,0.00532129,0.08276369,0.35857,0.5493886],"study_design_scores_gemma":[0.00002915902,0.000130948,0.006964365,0.0004938371,0.00003255988,0.001460933,0.0002452865,0.0003366478,0.0006069707,0.06557074,0.9241067,0.00002182247],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.00398575,0.887606,0.001804571,0.01144777,0.004538049,0.00001703376,0.0001978829,0.0000624825,0.09034048],"genre_scores_gemma":[0.03557447,0.6234166,0.003687043,0.007115814,0.009792474,0.00006449404,0.0002384849,0.00005015688,0.3200604],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.007650246,"threshold_uncertainty_score":0.02559268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04479164776410324,"score_gpt":0.2707188096802211,"score_spread":0.2259271619161178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}