{"id":"W4323348387","doi":"10.1002/acr2.11537","title":"Guselkumab, a Selective Interleukin‐23 p19 Subunit Inhibitor, Resolves Dactylitis in Patients With Active Psoriatic Arthritis: Pooled Results Through Week 52 From Two Phase 3 Studies","year":2023,"lang":"en","type":"article","venue":"ACR Open Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Institute of Infection and Immunity","funders":"Janssen Research and Development; Janssen Scientific Affairs","keywords":"Dactylitis; Psoriatic arthritis; Medicine; Internal medicine; Dermatology; Oncology; Immunology; Arthritis; Enthesitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01298637,0.001347526,0.006646699,0.001209557,0.0002953866,0.001644716,0.0005935562,0.0008756379,0.001343901],"category_scores_gemma":[0.009363516,0.0007989933,0.007884973,0.00161803,0.0003983678,0.0007100584,0.0006444287,0.0008036153,0.0001925142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004635715,"about_ca_system_score_gemma":0.000988217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006823237,"about_ca_topic_score_gemma":0.002318049,"domain_scores_codex":[0.9951379,0.002722314,0.0007310438,0.0004530053,0.0007641655,0.000191673],"domain_scores_gemma":[0.9934857,0.002827905,0.002353626,0.0004719754,0.0005610429,0.0002997358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4012684,0.001228499,0.04804522,0.01850808,0.3581539,0.00023667,0.0002356856,0.001697707,0.01239814,0.00008103771,0.002579801,0.155567],"study_design_scores_gemma":[0.1832913,0.06582996,0.2739239,0.001576773,0.4619297,0.0009767889,0.0001655523,0.00163808,0.003909235,0.0002636278,0.006318805,0.0001762376],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6694058,0.3201381,0.002861927,0.0004827601,0.0004030218,0.001490188,0.00322014,0.000299342,0.001698748],"genre_scores_gemma":[0.9610955,0.03373938,0.00156606,0.0004267701,0.0003498383,0.0005863217,0.001782273,0.00003429218,0.0004195572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01298637,"threshold_uncertainty_score":0.06867933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03291086867339284,"score_gpt":0.3385793045595027,"score_spread":0.3056684358861099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}