{"id":"W4323348901","doi":"10.1093/gerona/glad079","title":"Significant Acceleration of Regional Brain Aging and Atrophy After Mild Traumatic Brain Injury","year":2023,"lang":"en","type":"article","venue":"The Journals of Gerontology Series A","topic":"Traumatic Brain Injury and Neurovascular Disturbances","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Alzheimer's Drug Discovery Foundation; Johnson and Johnson Pharmaceutical Research and Development; Alzheimer's Association; National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; National Institute of Biomedical Imaging and Bioengineering; Janssen Alzheimer Immunotherapy Research And Development; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Atrophy; Insula; Brain size; Traumatic brain injury; Amygdala; Central sulcus; Magnetic resonance imaging; Superior temporal gyrus; Medicine; Brain aging; Psychology; Neuroscience; Internal medicine; Functional magnetic resonance imaging; Psychiatry; Radiology; Cognition","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002781261,0.0001491818,0.000129839,0.0008533163,0.0002186076,0.0002669888,0.0001404926,0.000199193,0.0009074892],"category_scores_gemma":[0.001549297,0.0001113241,0.0001492737,0.0003655273,0.000252351,0.000326787,0.000311586,0.0001643408,0.0001719664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001438552,"about_ca_system_score_gemma":0.0001100689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003636752,"about_ca_topic_score_gemma":0.004106898,"domain_scores_codex":[0.9998811,0.00002457643,0.00001319236,0.00003662262,0.00002611803,0.00001835396],"domain_scores_gemma":[0.9994001,0.00007371193,0.0003482655,0.00006401432,0.0000654606,0.00004845325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001437666,0.00001391303,0.990827,0.00001304286,0.00005191682,0.00008405727,0.0001508446,0.0000893292,0.001367878,0.00002832428,0.00007908131,0.007150737],"study_design_scores_gemma":[3.510415e-7,0.00002742485,0.9996288,7.558664e-7,0.000004018484,0.000154677,0.00002777807,0.00003150364,0.00007378317,0.00001144833,0.00003873447,7.23725e-7],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991583,0.0003783457,0.0001074501,0.00001168787,0.000002972657,0.000002292712,0.0001152363,0.000006577416,0.0002171044],"genre_scores_gemma":[0.999465,0.0001566942,0.0000807886,0.000005527652,0.000007255976,0.000001798548,0.0001406853,0.000001442691,0.00014067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003636752,"threshold_uncertainty_score":0.007231176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1045633847235198,"score_gpt":0.3476219871431411,"score_spread":0.2430586024196214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}