{"id":"W4323350197","doi":"10.1155/2023/2899271","title":"TIRAP, TRAM, and Toll-Like Receptors: The Untold Story","year":2023,"lang":"en","type":"review","venue":"Mediators of Inflammation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"TLR3; Proinflammatory cytokine; Receptor; Innate immune system; TRIF; Signal transducing adaptor protein; Pattern recognition receptor; Signal transduction; Cell biology; Toll-like receptor; Biology; Toll; Myeloid cells; Immunology; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007355595,0.0008862067,0.001158367,0.001733268,0.0003418615,0.00175462,0.0008900028,0.001719192,0.004134952],"category_scores_gemma":[0.000993326,0.0002572474,0.0004030412,0.002032863,0.0007738759,0.00353438,0.0009085537,0.003241924,0.003778428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006612363,"about_ca_system_score_gemma":0.001182801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006825461,"about_ca_topic_score_gemma":0.00083922,"domain_scores_codex":[0.9997956,0.00003435087,0.00002304102,0.00004012042,0.00008088302,0.00002596985],"domain_scores_gemma":[0.9995831,0.0001716638,0.0000438316,0.00001838839,0.0001159875,0.0000670593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001516428,0.00006481333,0.0001723247,0.01170794,0.00006573987,0.0004196298,0.0001395823,0.0002570242,0.003585649,0.01217522,0.09289971,0.8783607],"study_design_scores_gemma":[0.000005889823,0.00004645317,0.000223349,0.001244213,0.00002323774,0.0007997843,0.00005086803,0.00002884748,0.0002805281,0.002370331,0.994915,0.00001147652],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006144659,0.9973749,0.0000986654,0.0007938683,0.000910444,0.000001385786,0.00001050826,0.000006696852,0.0007421263],"genre_scores_gemma":[0.0005252424,0.9965964,0.0001422842,0.0006215035,0.0009840832,0.000003391263,0.00002433357,0.000002873487,0.001099745],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004134952,"threshold_uncertainty_score":0.01383281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02399735310691562,"score_gpt":0.280080372455523,"score_spread":0.2560830193486074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}