{"id":"W4323350197","doi":"10.1155/2023/2899271","title":"TIRAP, TRAM, and Toll-Like Receptors: The Untold Story","year":2023,"lang":"en","type":"review","venue":"Mediators of Inflammation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"TLR3; Proinflammatory cytokine; Receptor; Innate immune system; TRIF; Signal transducing adaptor protein; Pattern recognition receptor; Signal transduction; Cell biology; Toll-like receptor; Biology; Toll; Myeloid cells; Immunology; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001127457,0.000366402,0.001057272,0.0004222801,0.0002101834,0.00002253728,0.0003433359,0.000757253,0.0001269493],"category_scores_gemma":[0.0004920859,0.0002448543,0.0002875311,0.0003467429,0.0002836269,0.0001787493,0.0001040025,0.0006204596,0.0008508248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000710052,"about_ca_system_score_gemma":0.000248065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001871629,"about_ca_topic_score_gemma":0.00001644707,"domain_scores_codex":[0.9974074,0.0009512949,0.0009626588,0.0002896119,0.0001040596,0.0002849293],"domain_scores_gemma":[0.9974397,0.001066039,0.0009168807,0.0004664974,0.0000894728,0.00002136738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003270704,0.00001037249,0.00000442398,0.004249476,0.0003892894,0.000001736672,0.0008054212,4.957799e-7,0.0003364228,0.0005117065,0.008401754,0.9852562],"study_design_scores_gemma":[0.0002944716,0.00006167126,0.00002541274,0.002387026,0.0004267284,0.00002375629,0.0001730255,0.000001180771,0.0007280021,0.00003322578,0.9956092,0.000236313],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002025628,0.9938487,0.000008609774,0.0001386671,0.002761279,0.0009273231,0.00001559266,0.0001141664,0.0001599861],"genre_scores_gemma":[0.00006395572,0.9960474,0.000008153257,0.00001034968,0.0001981131,0.000172769,0.0006190301,0.00005189192,0.002828312],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9872074,"threshold_uncertainty_score":0.9999271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02399735310691562,"score_gpt":0.280080372455523,"score_spread":0.2560830193486074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}