{"id":"W4323351027","doi":"10.1093/jcag/gwac036.021","title":"A21 ROLE OF SIALIC ACID O-ACETYLATION IN MAINTAINING MUCUS INTEGRITY AND HOMEOSTASIS OF THE COLONIC MUCOSA","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Mucin; Mucus; Glycan; Sialidase; Sialic acid; Biochemistry; Chemistry; Microbiology; Mucin 2; Biology; Glycomics; Glycoprotein; Enzyme; Neuraminidase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001465549,0.0003234759,0.0001514359,0.0001980508,0.000205399,0.0004176126,0.0001653279,0.0002768095,0.001101771],"category_scores_gemma":[0.0001163571,0.0001360555,0.0002849319,0.0001596945,0.0002568345,0.0003319042,0.0002140638,0.0003683636,0.0002375696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002507264,"about_ca_system_score_gemma":0.0002770752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102494,"about_ca_topic_score_gemma":0.00121785,"domain_scores_codex":[0.9999018,0.00001641724,0.000006904638,0.00002374001,0.00002242757,0.00002867942],"domain_scores_gemma":[0.9998773,0.000006683247,0.00003232033,0.0000125958,0.00002437109,0.0000467583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000138595,0.000009447804,0.001512031,0.00005494716,0.00001032073,0.00004811334,0.00001228491,0.00002649409,0.996426,0.0001142977,0.00003030511,0.0016171],"study_design_scores_gemma":[0.00003415609,0.000790981,0.1426307,0.00005042636,0.00008349538,0.0008229491,0.0003126004,0.001992978,0.8450886,0.0004077625,0.007763003,0.00002228278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802616,0.011894,0.003974481,0.0003435218,0.00006348593,0.00002753258,0.0002893081,0.00005759099,0.003088586],"genre_scores_gemma":[0.9939318,0.002456297,0.001715835,0.0001006844,0.00001536424,0.00001409918,0.0001810993,0.00000832666,0.001576445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001101771,"threshold_uncertainty_score":0.003685772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008805211929809164,"score_gpt":0.2444704531300167,"score_spread":0.2356652412002075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}