{"id":"W4323351132","doi":"10.1093/jcag/gwac036.238","title":"A238 BILE ACID COMPOSITION AND DIETARY FAT: IMPLICATIONS FOR CROHN’S DISEASE IN A COHORT OF HEALTHY FIRST-DEGREE RELATIVES","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Ottawa; University of British Columbia; Hospital for Sick Children; University of Calgary; University of Alberta; McMaster University; University of Toronto","funders":"Crohn's and Colitis Canada; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Crohn's disease; Cohort; Disease; Bile acid; Microbiome; Internal medicine; Gastroenterology; Medicine; Etiology; First-degree relatives; Inflammatory bowel disease; Immunology; Biology; Family history; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005912055,0.0004472308,0.0004931451,0.0008805395,0.001003999,0.000600254,0.0003602894,0.0005114719,0.002409402],"category_scores_gemma":[0.002401544,0.0002849528,0.0005824663,0.00089053,0.000325978,0.0002817419,0.0004467806,0.0005796424,0.0002983709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003074188,"about_ca_system_score_gemma":0.0002587215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01313238,"about_ca_topic_score_gemma":0.009179922,"domain_scores_codex":[0.9995289,0.0001129566,0.00003845501,0.00017726,0.00005887852,0.00008354162],"domain_scores_gemma":[0.998956,0.0002757111,0.0002744425,0.0001536992,0.00007956201,0.0002605391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003432972,0.00004842503,0.9973551,0.000005807273,0.00005286345,0.0002874973,0.0001013349,0.00003776943,0.0007159508,0.00001970134,0.00006320117,0.0009690578],"study_design_scores_gemma":[0.00001213816,0.000147735,0.9980742,0.000005660517,0.00005787376,0.0008192167,0.0002284137,0.0002746713,0.000167174,0.00004353851,0.0001653071,0.000004203944],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994771,0.0001187345,0.00006975257,0.000021515,0.000003584631,0.000002992245,0.0001494175,0.00000261753,0.0001544331],"genre_scores_gemma":[0.9996504,0.00003895889,0.00006870239,0.000008951969,0.000003384728,0.000003034436,0.0001042683,0.000001444907,0.000120993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01313238,"threshold_uncertainty_score":0.02611184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293152159260966,"score_gpt":0.2504628137791435,"score_spread":0.2375312921865339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}