{"id":"W4323351204","doi":"10.1093/jcag/gwac036.051","title":"A51 INTESTINAL MICROBIOTA DETERMINES ARYL HYDROCARBON RECEPTOR ACTIVATION AND SUSCEPTIBILITY TO COLITIS","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aryl hydrocarbon receptor; Colitis; Dysbiosis; Immune system; Gut flora; Microbiology; Interleukin 22; Biology; Immunology; Cytokine; Gene; Biochemistry; Transcription factor; Interleukin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001247454,0.0002753587,0.0002956184,0.0005535349,0.0001488023,0.0003241316,0.0001021359,0.0003755465,0.003135776],"category_scores_gemma":[0.0003048413,0.0001988801,0.0002149707,0.0002964547,0.0001938986,0.0001576923,0.0002613724,0.0004629044,0.0004663532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000136656,"about_ca_system_score_gemma":0.0001095469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003582021,"about_ca_topic_score_gemma":0.0004889016,"domain_scores_codex":[0.9997885,0.00004162684,0.00001666269,0.00006083774,0.00003645222,0.00005587238],"domain_scores_gemma":[0.999346,0.00004553725,0.0002705508,0.00003846639,0.00004035612,0.0002590924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002723232,0.0002839887,0.08813227,0.00004079063,0.0000499589,0.0002147609,0.00004006012,0.00003430126,0.906036,0.00004726974,0.0001269352,0.002270343],"study_design_scores_gemma":[0.00002695579,0.0009511069,0.9612893,0.00001499154,0.00004892332,0.001124734,0.0001271533,0.0003257332,0.03549619,0.00007284139,0.0005130715,0.000008891569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990354,0.0002456883,0.0001650659,0.00002385935,0.000004924927,0.000006816503,0.0002098124,0.00001142105,0.0002971643],"genre_scores_gemma":[0.998805,0.0001394224,0.0002901975,0.0000287689,0.000005235434,0.00001116547,0.000251951,0.000009553043,0.0004586534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003135776,"threshold_uncertainty_score":0.01049018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007543181162571538,"score_gpt":0.2310210390643604,"score_spread":0.2234778579017889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}