{"id":"W4323351226","doi":"10.1093/jcag/gwac036.153","title":"A153 PYCRL LACTYLATION AS A POTENTIAL REGULATOR OF CANCER STEM CELL METABOLISM IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Cancer stem cell; Esophageal cancer; Cancer research; Cancer; Radiation therapy; Stem cell; Malignancy; Cell; Medicine; Oncology; Cancer cell; Chemotherapy; Cell culture; Flow cytometry; Internal medicine; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141584,0.0002945693,0.000301003,0.0002584521,0.0001900872,0.0003288187,0.0001491037,0.0002548577,0.001299418],"category_scores_gemma":[0.00007987255,0.0001084437,0.0004473924,0.0002711389,0.0001605183,0.0001837571,0.0001876342,0.0003191604,0.0004105442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003083366,"about_ca_system_score_gemma":0.0002364262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006045417,"about_ca_topic_score_gemma":0.0008354381,"domain_scores_codex":[0.9999282,0.000009692157,0.000006696022,0.00002128387,0.00001770031,0.00001647175],"domain_scores_gemma":[0.9999599,0.000004412719,0.00001451271,0.000003663464,0.000006659818,0.00001069876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004004528,0.00003377072,0.001392417,0.0001238877,0.00001850894,0.0001124947,0.00001331643,0.0001913334,0.9950448,0.00008422411,0.0001349127,0.002449876],"study_design_scores_gemma":[0.00008489284,0.000801374,0.04710304,0.00002937813,0.0001216493,0.0006298694,0.0001240693,0.004544749,0.9396174,0.000159649,0.006761877,0.00002205676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892522,0.005084786,0.002264213,0.0002681258,0.00004712457,0.00003473157,0.001848243,0.0001249842,0.001075542],"genre_scores_gemma":[0.9910331,0.001824885,0.002212694,0.0001370984,0.000009889488,0.00004666096,0.002474618,0.00001614083,0.002244801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001299418,"threshold_uncertainty_score":0.004346967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004958286069828526,"score_gpt":0.2120837532722925,"score_spread":0.2071254672024639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}