{"id":"W4323351253","doi":"10.1093/jcag/gwac036.279","title":"A279 EVIDENCE OF TRANSIENT RECEPTOR POTENTIAL MELASTATIN 3 (TRPM3) CHANNEL SENSITIZATION IN A MOUSE MODEL OF COLITIS","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Transient receptor potential channel; Colitis; Medicine; TRPV1; Extracellular; Visceral pain; Intracellular; Endocrinology; Internal medicine; Sensitization; Inflammatory bowel disease; Chemistry; Receptor; Nociception; Immunology; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003855063,0.0007696637,0.0006922474,0.001137974,0.0003948861,0.0004954424,0.0005698408,0.001497891,0.005615705],"category_scores_gemma":[0.0002127715,0.0004308069,0.001172514,0.000440864,0.0008545329,0.0007023601,0.0003433499,0.002998457,0.001569288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006021228,"about_ca_system_score_gemma":0.0003896295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008482913,"about_ca_topic_score_gemma":0.001016745,"domain_scores_codex":[0.9993346,0.00006941676,0.000071586,0.000183933,0.0001870281,0.0001533442],"domain_scores_gemma":[0.9995021,0.00004559056,0.0001462794,0.00005121951,0.00004402897,0.0002107302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005018335,0.0001421131,0.0001258395,0.00006707408,0.00001217951,0.0001923701,0.00002254928,0.00004813689,0.9979268,0.0001301735,0.0001527777,0.0006782155],"study_design_scores_gemma":[0.000189677,0.002472711,0.007580187,0.00005905789,0.00006009155,0.001238229,0.0001664789,0.002207487,0.9819493,0.0003692794,0.003678362,0.00002921744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741502,0.002847551,0.009604384,0.001487356,0.0004617915,0.0002087186,0.004206172,0.0007539528,0.006279702],"genre_scores_gemma":[0.9722367,0.002126213,0.00629527,0.0007113781,0.00006353709,0.0005032656,0.001845169,0.0001795959,0.01603885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005615705,"threshold_uncertainty_score":0.01878643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02451812754572932,"score_gpt":0.2409868665118061,"score_spread":0.2164687389660768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}