{"id":"W4323353284","doi":"10.1093/jcag/gwac036.007","title":"A7 OPPORTUNISTIC PATHOGEN MODULATION OF GLUTEN-REACTIVE CD4+ T CELL ACTIVATION BY DQ2-EXPRESSING ORGANOID MONOLAYERS","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Elastase; Chemistry; Gluten; Microbiology; T cell; Molecular biology; Biochemistry; Immune system; Biology; Immunology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001131754,0.000364746,0.0002876521,0.0001246279,0.0001335079,0.0003532149,0.0001393816,0.000275272,0.003709472],"category_scores_gemma":[0.0000868848,0.0001117464,0.000237774,0.0001122966,0.0001307343,0.0001683708,0.0002130805,0.0006128489,0.0006660872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001336439,"about_ca_system_score_gemma":0.00006889264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002321833,"about_ca_topic_score_gemma":0.0002667178,"domain_scores_codex":[0.9997439,0.00006299499,0.0000220383,0.00006033537,0.00004843781,0.00006232457],"domain_scores_gemma":[0.9999104,0.0000171212,0.00001751783,0.00001654518,0.00001322668,0.00002517059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000154597,0.00003049423,0.000115197,0.00002387679,0.000002162494,0.00003272743,0.00001450184,0.00002064471,0.9992527,0.00001242288,0.00002350164,0.0003171478],"study_design_scores_gemma":[0.0000455115,0.001711115,0.005461242,0.0000100385,0.00002191851,0.0002578078,0.0001579619,0.0009396197,0.9886983,0.00003814862,0.002652181,0.000006125868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996554,0.0005582476,0.001273482,0.00004227101,0.00004696491,0.00003367578,0.0002417043,0.00002838212,0.001221397],"genre_scores_gemma":[0.9953055,0.000304711,0.001665136,0.00007290738,0.00001759155,0.0000477775,0.0004536787,0.000009095082,0.002123543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003709472,"threshold_uncertainty_score":0.01240939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01312137048851597,"score_gpt":0.2456879000441981,"score_spread":0.2325665295556821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}