{"id":"W4323353304","doi":"10.1093/jcag/gwac036.227","title":"A227 CTLA-4 DEFICIENCY PRESENTING AS CROHN DISEASE IN A TEENAGE BOY WITH MULTI-SYSTEM INVOLVEMENT : A CASE REPORT","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Medicine; Immune dysregulation; Inflammatory bowel disease; Immunology; Immunodeficiency; Hypogammaglobulinemia; Internal medicine; Hemophagocytic lymphohistiocytosis; Gastroenterology; Immune system; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003876978,0.002830269,0.001880398,0.003567214,0.003167106,0.001992199,0.001165007,0.005451811,0.004166462],"category_scores_gemma":[0.002171984,0.001838125,0.001542758,0.001856993,0.001340398,0.002244757,0.002160328,0.00400066,0.001146179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001099138,"about_ca_system_score_gemma":0.0009659588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002646072,"about_ca_topic_score_gemma":0.003060286,"domain_scores_codex":[0.9990813,0.0001099989,0.0001053591,0.0002572106,0.0001137529,0.0003323902],"domain_scores_gemma":[0.9984385,0.0003650586,0.0003543312,0.00007840391,0.0001012158,0.0006624614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.000008525187,0.00003343152,0.005643299,0.00001664195,0.000005659362,0.9933444,0.0001083804,0.00001901342,0.0002113594,0.00005772946,0.00016898,0.0003824914],"study_design_scores_gemma":[0.000005372608,0.00003809646,0.003247791,0.00001769696,0.000009053269,0.9960389,0.0001108133,0.00008820309,0.00007769855,0.00004237159,0.000317893,0.000006009764],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777949,0.006726774,0.002764496,0.003594747,0.000570708,0.0001778627,0.0003912723,0.0001895441,0.007789737],"genre_scores_gemma":[0.992934,0.002347929,0.001424954,0.0009080236,0.0006781343,0.00004329409,0.0001460595,0.00003943814,0.001478253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005451811,"threshold_uncertainty_score":0.01393819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00982187406007431,"score_gpt":0.2224561182448188,"score_spread":0.2126342441847444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}