{"id":"W4323353325","doi":"10.1093/jcag/gwac036.275","title":"A275 MECHANOSENSITIVE KCA2 + 1.1 CHANNEL MEDIATES INTRALUMINAL DISTENSION-INDUCED CALCIUM INFLUX IN ENTERIC NEURONS","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Enteric nervous system; Distension; Myenteric plexus; Mechanosensitive channels; Biology; Anatomy; Perfusion; Internal medicine; Chemistry; Endocrinology; Medicine; Biochemistry; Immunohistochemistry; Immunology; Ion channel","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001853438,0.0002576915,0.0004132044,0.0001939461,0.0002947898,0.0003694583,0.0003745367,0.0004561937,0.00229347],"category_scores_gemma":[0.0001720073,0.0001325114,0.0004028253,0.0001702997,0.0003421344,0.000391613,0.0003003631,0.0005454812,0.0007177435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003885447,"about_ca_system_score_gemma":0.0003757548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007834578,"about_ca_topic_score_gemma":0.0009637801,"domain_scores_codex":[0.9998177,0.0000115861,0.00001987733,0.00004619396,0.00004787885,0.00005678384],"domain_scores_gemma":[0.9998902,0.00001449424,0.00002488619,0.0000127058,0.00002086832,0.00003683487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001250825,0.00001260894,0.0001756048,0.0000726182,0.000003317227,0.00006819525,0.00001473912,0.0000271081,0.9989814,0.0000881291,0.00004485292,0.0003863683],"study_design_scores_gemma":[0.00008800003,0.0002714547,0.02653166,0.00004060844,0.00003187518,0.0005492606,0.0001641591,0.00241712,0.9665679,0.0002114608,0.003110018,0.00001637948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887642,0.002323179,0.005022218,0.0002359844,0.00006196172,0.00004666788,0.0007297571,0.000121126,0.002694926],"genre_scores_gemma":[0.9928125,0.001032632,0.002320035,0.0001061696,0.00001733717,0.00009960081,0.0005702854,0.00002876118,0.003012738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00229347,"threshold_uncertainty_score":0.007672429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963486267611628,"score_gpt":0.2490951287831131,"score_spread":0.2294602661069968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}