{"id":"W4323353416","doi":"10.1016/s2468-1253(23)00007-9","title":"Reset after RESET: insights from a negative trial in coeliac disease","year":2023,"lang":"en","type":"letter","venue":"The Lancet. Gastroenterology & hepatology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Coeliac disease; Medicine; Gluten; Gluten free; Disease; Immunology; Gastroenterology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02408799,0.0007700873,0.001756241,0.0006131685,0.002668002,0.005313326,0.002720253,0.03746529,0.009650399],"category_scores_gemma":[0.1140363,0.0004605868,0.001528915,0.0008862613,0.003767176,0.005429516,0.002418044,0.02578397,0.005171422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004029218,"about_ca_system_score_gemma":0.004650762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003585176,"about_ca_topic_score_gemma":0.006345223,"domain_scores_codex":[0.981948,0.01291347,0.001016479,0.0007508993,0.002218048,0.00115309],"domain_scores_gemma":[0.9078682,0.07396265,0.003553228,0.001898041,0.00467785,0.008040082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001312317,0.00006757873,0.001082926,0.0003072466,0.0001294177,0.00153225,0.0002790566,0.0001067193,0.0002750338,0.005966772,0.9453,0.04364068],"study_design_scores_gemma":[0.004005091,0.001000033,0.004454473,0.002484207,0.0003361,0.002108477,0.0009471948,0.0005394607,0.0004767374,0.04339803,0.9400955,0.0001545925],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0008496916,0.01131371,0.00008622957,0.9752203,0.008267893,0.00001189741,0.0001055707,0.00002445462,0.004120273],"genre_scores_gemma":[0.01399158,0.00486153,0.0001929551,0.9453231,0.03285507,0.00006688885,0.00006931905,0.00004748493,0.00259209],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03746529,"threshold_uncertainty_score":0.127391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03785468419480562,"score_gpt":0.311277184523192,"score_spread":0.2734225003283864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}