{"id":"W4323353479","doi":"10.1093/jcag/gwac036.172","title":"A172 THE LACK OF CHROMOGRANIN A PROTECTS THE COLONIC EPITHELIAL BARRIER FUNCTIONS FROM COLITIS IN MALE MICE AND EXACERBATES COLITIS IN FEMALE MICE","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Biochemical Analysis and Sensing Techniques","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Colitis; Chromogranin A; Barrier function; Mucin; Internal medicine; Inflammatory bowel disease; Ulcerative colitis; Medicine; Endocrinology; Andrology; Biology; Immunology; Pathology; Immunohistochemistry; Disease; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002112167,0.0007451429,0.0005346651,0.001156888,0.0002822167,0.0004669923,0.0003589923,0.0006534458,0.006686336],"category_scores_gemma":[0.0001200076,0.0004628726,0.0006089053,0.000274012,0.0005547312,0.0004024041,0.0003541607,0.001679318,0.001706358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002651269,"about_ca_system_score_gemma":0.0003650737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000541859,"about_ca_topic_score_gemma":0.000717842,"domain_scores_codex":[0.999604,0.00004686121,0.00003804576,0.000102747,0.00009592692,0.0001124136],"domain_scores_gemma":[0.99935,0.0000246794,0.0002173645,0.00005164198,0.00003309149,0.0003231326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009508981,0.000215863,0.0007320294,0.00005822577,0.00001958613,0.0001292919,0.00001905476,0.00003104267,0.9960521,0.00011947,0.0001708122,0.00150172],"study_design_scores_gemma":[0.0003870795,0.00571237,0.04114049,0.00009161281,0.000136267,0.002193899,0.0002643891,0.0007727768,0.9397839,0.0002408123,0.00923915,0.00003726509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989917,0.002383939,0.002134657,0.0004961058,0.0002107979,0.00007303839,0.002047925,0.0003223352,0.002414264],"genre_scores_gemma":[0.9739335,0.001852856,0.002119198,0.0004237806,0.00008664639,0.000220358,0.001877959,0.0001825939,0.01930308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006686336,"threshold_uncertainty_score":0.02236801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377542458843455,"score_gpt":0.2373116247775919,"score_spread":0.2235362001891573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}