{"id":"W4323540165","doi":"10.1007/s12022-023-09753-5","title":"Update on C-Cell Neuroendocrine Neoplasm: Prognostic and Predictive Histopathologic and Molecular Features of Medullary Thyroid Carcinoma","year":2023,"lang":"en","type":"review","venue":"Endocrine Pathology","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Research Foundation of Korea","keywords":"Pathology; Medicine; Thyroid; Thyroid carcinoma; Neuroendocrine tumors; Thyroid neoplasm; Neoplasm; Medullary thyroid cancer; Thyroid cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008859995,0.0006932017,0.001728192,0.002530142,0.0001954912,0.001130815,0.001135367,0.0008941648,0.002852146],"category_scores_gemma":[0.001734562,0.0002882344,0.0008886864,0.002492125,0.0003650295,0.00131904,0.0006672388,0.001604191,0.001254696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006270076,"about_ca_system_score_gemma":0.001359842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001722494,"about_ca_topic_score_gemma":0.004336502,"domain_scores_codex":[0.9997265,0.00005082481,0.00006407187,0.0000455463,0.000090179,0.00002278243],"domain_scores_gemma":[0.9990901,0.0004850435,0.0001302984,0.00001833958,0.000218595,0.00005768288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001006167,0.00004473859,0.0008665386,0.02113224,0.0002924417,0.0004719579,0.00006421336,0.0003455632,0.000934277,0.0008456015,0.06711461,0.9077871],"study_design_scores_gemma":[0.00007030263,0.0001518473,0.003947494,0.01291,0.001309778,0.00407092,0.00009760219,0.0002323888,0.000296701,0.001138418,0.9757243,0.00005027725],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001693344,0.9983025,0.0001344399,0.000432093,0.0003518246,0.000005378028,0.0000685324,0.000009959397,0.0005259098],"genre_scores_gemma":[0.0009337332,0.9969729,0.00032341,0.0006919501,0.0005691747,0.000006381692,0.0001361321,0.000002042775,0.0003642388],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002852146,"threshold_uncertainty_score":0.009541392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095389627093501,"score_gpt":0.2962450977832005,"score_spread":0.2752912015122654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}