{"id":"W4323567714","doi":"10.3389/fpsyt.2023.1039239","title":"Longitudinal progression of choroid plexus enlargement is associated with female sex, cognitive decline and ApoE E4 homozygote status","year":2023,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Ministerstvo Školství, Mládeže a Tělovýchovy; Northern California Institute for Research and Education; DoD Alzheimer's Disease Neuroimaging Initiative; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; Grantová Agentura, Univerzita Karlova; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Meso Scale Diagnostics; Alzheimer's Association; Univerzita Karlova v Praze; Foundation for the National Institutes of Health","keywords":"Confidence interval; Apolipoprotein E; Internal medicine; Medicine; Cohort; Dementia; Endocrinology; Psychology; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007751868,0.0002586305,0.0002548936,0.0005993441,0.0002369879,0.0004225423,0.0002029208,0.000361952,0.00236572],"category_scores_gemma":[0.001963647,0.0002110072,0.0003420384,0.0004254916,0.0002520288,0.0003328901,0.0003099411,0.0003146422,0.0002248835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001267042,"about_ca_system_score_gemma":0.0001965493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003723898,"about_ca_topic_score_gemma":0.003568891,"domain_scores_codex":[0.9997858,0.00004833624,0.00001842386,0.00008799775,0.00002593248,0.00003342475],"domain_scores_gemma":[0.9988563,0.0002328984,0.0005408588,0.0001407753,0.000108286,0.0001209651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004778499,0.00001203523,0.995538,0.000006244891,0.00006681105,0.0001046399,0.0000665942,0.0000363548,0.001284636,0.00001628559,0.00006415415,0.002326413],"study_design_scores_gemma":[0.000002974499,0.0000542986,0.9993636,0.000002247167,0.00001684744,0.0002391299,0.00003794429,0.00008087135,0.00009562109,0.00002542779,0.00007935867,0.000001627741],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988093,0.0003427408,0.000194661,0.00002684513,0.000003462056,0.000003266101,0.0003219347,0.000008865594,0.0002888023],"genre_scores_gemma":[0.9991881,0.00008795722,0.0001289058,0.00001055016,0.000006315645,0.000004349054,0.0002439659,0.000003005626,0.0003268531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003723898,"threshold_uncertainty_score":0.007914066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01503635375997878,"score_gpt":0.325221167524227,"score_spread":0.3101848137642482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}