{"id":"W4323656857","doi":"10.1002/anie.202300211","title":"Enantioselective Rhodium‐Catalyzed Pauson–Khand Reactions of 1,6‐Chloroenynes with 1,1‐Disubstituted Olefins","year":2023,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Institute for Basic Science; Queen's University; Hunan Provincial Science and Technology Department","keywords":"Enantioselective synthesis; Rhodium; Pauson–Khand reaction; Catalysis; Chemistry; Medicinal chemistry; Organic chemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001168344,0.0002183206,0.0002342617,0.0002648472,0.0001359869,0.0000443155,0.000237505,0.000135574,0.0009395655],"category_scores_gemma":[0.0002771459,0.0002058375,0.0001322273,0.0005921107,0.0001702152,0.0004822822,0.00006087666,0.0002365669,0.0001336567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002725669,"about_ca_system_score_gemma":0.000127117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003188197,"about_ca_topic_score_gemma":0.0001862602,"domain_scores_codex":[0.9984154,0.000006228586,0.0003862386,0.0003847748,0.000548347,0.0002590108],"domain_scores_gemma":[0.9985862,0.0002244964,0.0003063925,0.0002978623,0.0004928969,0.00009210367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001762759,0.0002280939,0.001051724,0.00008804313,0.0004272266,0.00002697617,0.0002742151,0.00009192856,0.9892083,0.0008899388,0.007146302,0.0003909199],"study_design_scores_gemma":[0.0009358661,0.00001794688,0.002143166,0.0001876525,0.0001001241,0.00009169785,0.0004750071,0.0001656879,0.9789713,0.0005839217,0.01610374,0.0002238779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9175224,0.00005541668,0.004167777,0.001550089,0.00137097,0.0002253466,0.001319817,0.0007622273,0.07302599],"genre_scores_gemma":[0.9899517,0.0001679198,0.0001388822,0.00001835508,0.0009111055,0.0001218494,0.004762245,0.00003900523,0.003888976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07242929,"threshold_uncertainty_score":0.9999737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01608415536895018,"score_gpt":0.2593661818033839,"score_spread":0.2432820264344338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}