{"id":"W4323667588","doi":"10.3390/antiox12030671","title":"Dysregulated Iron Homeostasis as Common Disease Etiology and Promising Therapeutic Target","year":2023,"lang":"en","type":"review","venue":"Antioxidants","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Hepcidin; Reactive oxygen species; Cancer; Biology; Chemistry; Cancer research; Inflammation; Immunology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000287719,0.0005318041,0.0008698181,0.001581354,0.0002276458,0.00064991,0.0005318692,0.0008059181,0.004144562],"category_scores_gemma":[0.0003866312,0.0001387317,0.0002770989,0.001265873,0.0002728119,0.0007909001,0.0005173972,0.001176563,0.00192716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004251774,"about_ca_system_score_gemma":0.0008057837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006634222,"about_ca_topic_score_gemma":0.001263024,"domain_scores_codex":[0.9999171,0.00001529251,0.00001155952,0.00001697386,0.00002681863,0.0000121621],"domain_scores_gemma":[0.9998649,0.0000540538,0.00002072002,0.000004109849,0.00003905927,0.00001709417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009524768,0.00006370346,0.0002163963,0.01420031,0.00006992581,0.0004761358,0.00005896452,0.0002701819,0.002257339,0.004649336,0.05766825,0.9199741],"study_design_scores_gemma":[0.00001295353,0.00007749558,0.0007613347,0.003638707,0.00008465561,0.002709009,0.0000563414,0.0001092593,0.0004250964,0.002624257,0.9894876,0.00001332262],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001089413,0.9983808,0.0001002603,0.0003105544,0.0002056426,0.000002536922,0.00001635975,0.0000082495,0.000866616],"genre_scores_gemma":[0.0008751752,0.9977464,0.0001487027,0.0002318429,0.0002243467,0.000004572393,0.00003810943,0.000001986696,0.0007289253],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004144562,"threshold_uncertainty_score":0.01386487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05218375987030637,"score_gpt":0.3641692631628383,"score_spread":0.3119855032925319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}