{"id":"W4323812027","doi":"10.1080/21678421.2023.2173015","title":"Clinical testing panels for ALS: global distribution, consistency, and challenges","year":2023,"lang":"en","type":"review","venue":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; Western University; McGill University","funders":"National Health and Medical Research Council; Medical Research Council; National Institutes of Health; Prinses Beatrix Spierfonds; National Human Genome Research Institute; ALS Association; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institute for Health and Care Research; Motor Neurone Disease Association; Muscular Dystrophy Association; Johns Hopkins University; Microsoft Research; Motor Neurone Disease Australia; GlaxoSmithKline","keywords":"Consistency (knowledge bases); Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001341282,0.000797383,0.002809007,0.00009895078,0.0004922082,0.0002861574,0.0001888277,0.001016676,0.00001504174],"category_scores_gemma":[0.0006051206,0.0005948908,0.0005575203,0.0003290448,0.000423963,0.0002773118,0.0002766917,0.0005137628,0.00003319298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003430002,"about_ca_system_score_gemma":0.0003963949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003487087,"about_ca_topic_score_gemma":0.00006647218,"domain_scores_codex":[0.9948304,0.0004922086,0.001895484,0.001444096,0.0005298528,0.0008079933],"domain_scores_gemma":[0.9973928,0.0004329033,0.0005882471,0.0005321111,0.0004260657,0.0006278281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009009335,0.0001067579,0.001426205,0.009884597,0.0004143148,0.00002273464,0.00003159354,6.835691e-7,0.00002075695,0.001088032,0.0007085023,0.9862058],"study_design_scores_gemma":[0.005880696,0.003591764,0.2529339,0.0372225,0.004474746,0.0004090116,0.00003371471,0.002626059,0.000002272134,0.002266827,0.6880944,0.002464079],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008715546,0.9853407,0.0001952282,0.001232915,0.0004679134,0.002861343,0.000904475,0.0002328277,0.00004905702],"genre_scores_gemma":[0.007529564,0.986154,0.001871187,0.0001032964,0.001490857,0.0005414582,0.001929677,0.0001177901,0.0002622201],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9837416,"threshold_uncertainty_score":0.9996502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.455133256512144,"score_gpt":0.4218334896115044,"score_spread":0.03329976690063963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}