{"id":"W4323825230","doi":"10.1021/acsphotonics.2c01644","title":"Simultaneous Widefield Voltage and Dye-Free Optical Mapping Quantifies Electromechanical Waves in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes","year":2023,"lang":"en","type":"article","venue":"ACS Photonics","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Biomedical Imaging and Bioengineering; National Heart, Lung, and Blood Institute; National Institutes of Health; National Science Foundation","keywords":"Optical mapping; Voltage-sensitive dye; Wavefront; Materials science; Capacitive sensing; Biomedical engineering; Optoelectronics; Induced pluripotent stem cell; Optics; Physics; Computer science; Chemistry; Optical imaging; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001621306,0.0002052126,0.0001041381,0.0002357869,0.00007323494,0.0002138543,0.0001856535,0.0002299851,0.000303063],"category_scores_gemma":[0.0002083452,0.0001021658,0.00009730813,0.0001403771,0.0002201118,0.0002595692,0.0002732034,0.0004079743,0.00008345767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001552445,"about_ca_system_score_gemma":0.0001262178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001997339,"about_ca_topic_score_gemma":0.0004133212,"domain_scores_codex":[0.9998711,0.0000128727,0.000007632992,0.00003622391,0.00005831105,0.00001384828],"domain_scores_gemma":[0.9998745,0.00003970786,0.00003857403,0.00001178598,0.00002065712,0.00001475683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001260338,0.000004345849,0.000167599,0.00001139145,0.000001195385,0.00001164536,0.000009737307,0.00005118524,0.9974161,0.00006698103,0.00000822276,0.002238883],"study_design_scores_gemma":[0.000004015058,0.00009888397,0.007069066,0.000003387249,0.000006394615,0.0001168982,0.00002520953,0.001922503,0.990146,0.0001108002,0.0004916674,0.000005131924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9415448,0.001412605,0.05546152,0.00008379496,0.00002316677,0.00003029581,0.0002041634,0.0001061569,0.001133553],"genre_scores_gemma":[0.9723396,0.00106034,0.02517487,0.00006738937,0.00001689426,0.00006018479,0.0001782331,0.00002167398,0.001080833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000303063,"threshold_uncertainty_score":0.001126349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01872822217603572,"score_gpt":0.2541635131935882,"score_spread":0.2354352910175525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}