{"id":"W4323848621","doi":"10.3390/nu15061350","title":"Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials","year":2023,"lang":"en","type":"review","venue":"Nutrients","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Meta-analysis; Medicine; Chronic pain; Randomized controlled trial; Placebo; MEDLINE; Systematic review; Quality of life (healthcare); Palmitoylethanolamide; Physical therapy; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":["metaepi_broad"],"category_scores_codex":[0.03667781,0.0006008342,0.07651636,0.0014857,0.00003142017,0.0000283139,0.0003038131,0.0002627362,0.0001822593],"category_scores_gemma":[0.005588164,0.0002203338,0.01859944,0.002922666,0.0001776321,0.00001947319,0.00003567986,0.000232276,0.00000562957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002572468,"about_ca_system_score_gemma":0.0005516296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001264066,"about_ca_topic_score_gemma":0.00003259741,"domain_scores_codex":[0.9795321,0.01227812,0.006150481,0.0005026574,0.001195491,0.0003412144],"domain_scores_gemma":[0.9899161,0.004954662,0.003528204,0.001165066,0.000326802,0.0001091927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01399962,0.0004808001,1.894912e-7,0.6365131,0.3477754,0.00001740767,0.00009266289,1.480034e-7,6.489773e-8,0.0000325576,0.0002261961,0.0008619381],"study_design_scores_gemma":[0.2314968,0.0003320199,1.147489e-7,0.05119943,0.7066686,0.000004917461,0.00002227953,0.000008529839,5.668351e-7,0.000004662543,0.01016096,0.0001010691],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000008900371,0.9418634,0.000003492039,0.0007057424,0.00003180509,0.05719143,0.0001341405,0.000009005029,0.00005206609],"genre_scores_gemma":[0.00002887071,0.9668242,0.000002109872,0.00006008533,0.00004305805,0.02896223,0.0001864286,0.00003877972,0.003854188],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5853136,"threshold_uncertainty_score":0.9919429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2440983900268701,"score_gpt":0.4566017862840105,"score_spread":0.2125033962571404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}