{"id":"W4323858338","doi":"10.3389/fcell.2023.1153174","title":"Mitochondrial DNA abnormalities and metabolic syndrome","year":2023,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"China Medical University; Natural Science Foundation of Liaoning Province; Queen's University; National Natural Science Foundation of China","keywords":"Mitochondrial DNA; Biology; Mitochondrial disease; Mitochondrion; Disease; Bioinformatics; Genetics; Metabolic syndrome; Human mitochondrial genetics; DNAJA3; Gene; mitochondrial fusion; Medicine; Diabetes mellitus; Pathology; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000312398,0.0008122656,0.0009819387,0.00178868,0.0002812122,0.0007571478,0.000587637,0.0009821053,0.003779909],"category_scores_gemma":[0.0007168715,0.0001727286,0.0003603375,0.001450256,0.0003956585,0.0007952285,0.0006865325,0.001497736,0.001849868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006461787,"about_ca_system_score_gemma":0.000880842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001157294,"about_ca_topic_score_gemma":0.0017173,"domain_scores_codex":[0.9998295,0.0000305029,0.00002376085,0.00003071741,0.00006446696,0.00002105944],"domain_scores_gemma":[0.9997866,0.00009217546,0.00002972206,0.000005929526,0.00006588287,0.00001979034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008822443,0.00004231916,0.0003559994,0.01201745,0.00008627075,0.0005436233,0.0000660788,0.0003260054,0.00212172,0.004478353,0.05410212,0.9257718],"study_design_scores_gemma":[0.00001768956,0.00007110438,0.001616189,0.00437882,0.0001033647,0.005409762,0.00006759511,0.0001003249,0.0006173819,0.003725591,0.983869,0.00002318756],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001059927,0.9979164,0.0001551821,0.0003626823,0.0003286859,0.000003135278,0.00002175858,0.00001098757,0.001095191],"genre_scores_gemma":[0.0010588,0.997329,0.0001549995,0.0002441507,0.0002523399,0.000004665441,0.0000630311,0.000002084615,0.0008909965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003779909,"threshold_uncertainty_score":0.01264507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02146295224976058,"score_gpt":0.2603681248381432,"score_spread":0.2389051725883826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}