{"id":"W4323920878","doi":"10.1093/jambio/lxad047","title":"Transcriptome analysis of the <i>Clostridioides difficile</i> response to a specific lactobacilli probiotic formulation: explanations for its mechanisms of action","year":2023,"lang":"en","type":"article","venue":"Journal of Applied Microbiology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bio-K+ International (Canada); Ministère de l'Agriculture, des Pêcheries et de l'Alimentation; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Clostridioides; Probiotic; Transcriptome; Action (physics); Microbiology; Biology; Bacteria; Gene expression; Gene; Genetics; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009322562,0.0001628458,0.0007353894,0.001210458,0.00008799586,0.000008731144,0.0002440706,0.0001698869,0.00006504421],"category_scores_gemma":[0.0001837286,0.0001141415,0.0005550045,0.002534757,0.00006697889,0.00003521545,0.00004509126,0.0002357817,0.000008179557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001990947,"about_ca_system_score_gemma":0.0002733356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002256399,"about_ca_topic_score_gemma":0.00000997909,"domain_scores_codex":[0.9982857,0.00007579916,0.000902653,0.0002050391,0.0002307183,0.0003001009],"domain_scores_gemma":[0.9980262,0.0004845225,0.000482133,0.0002901184,0.0006144932,0.0001025201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006337473,0.0001912964,0.00002787879,0.00008968314,0.0007305675,0.000002966719,0.0003961238,0.001469773,0.9880303,0.0009517937,0.001350765,0.0004213509],"study_design_scores_gemma":[0.001718919,0.0007996029,0.001243435,0.00006119881,0.0008590043,0.00004267008,0.0006864996,0.00008380781,0.9874971,0.00007502922,0.00683739,0.00009536417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941469,0.00006731287,0.002194047,0.00200529,0.0002097789,0.0009398089,0.0003612556,0.0000140524,0.0000615807],"genre_scores_gemma":[0.9988807,0.00009623264,0.0005728871,0.00007403473,0.00008067135,0.00002145061,0.00006793092,0.00001960717,0.0001865137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005486625,"threshold_uncertainty_score":0.4654556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04985665722104776,"score_gpt":0.3135906389032199,"score_spread":0.2637339816821721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}