{"id":"W4323928256","doi":"10.1016/j.blre.2023.101072","title":"Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1st International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS)","year":2023,"lang":"en","type":"review","venue":"Blood Reviews","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre","funders":"Foundation Medicine; Takeda Oncology; Genentech; National Institutes of Health; Associazione Italiana per la Ricerca sul Cancro; Fondazione Italiana per la Ricerca sul Cancro; Astellas Pharma; Daiichi-Sankyo; MacroGenics; Pfizer; Incyte; CTI Biopharma; bluebird bio; Agios Pharmaceuticals; Alexion Pharmaceuticals; Apellis Pharmaceuticals; Celgene; BioCryst; Syndax Pharmaceuticals; National Heart, Lung, and Blood Institute; Edward P. Evans Foundation; Acceleron; Loxo Oncology; Astex Pharmaceuticals; Leukemia and Lymphoma Society; Daiichi Sankyo Europe; Servier; Gilead Sciences; Jazz Pharmaceuticals; Bristol-Myers Squibb; AstraZeneca; Cardinal Health; Amgen","keywords":"Myelodysplastic syndromes; Medicine; Clinical trial; Epigenetics; Disease; Translational research; Bioinformatics; Immunology; Biology; Internal medicine; Genetics; Gene; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006467747,0.001159721,0.003399245,0.003164636,0.000469603,0.003736915,0.001505989,0.002839477,0.005636091],"category_scores_gemma":[0.00675049,0.0005182748,0.001219275,0.003783611,0.0008926785,0.00343014,0.001920719,0.003812166,0.002148379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001933148,"about_ca_system_score_gemma":0.005748829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002101434,"about_ca_topic_score_gemma":0.005545279,"domain_scores_codex":[0.9987393,0.000349341,0.0002221618,0.0001291306,0.0004369574,0.0001231663],"domain_scores_gemma":[0.9942269,0.003417453,0.0004977274,0.00008463545,0.001408595,0.0003646691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002282955,0.00007657838,0.0001891967,0.04874342,0.0002253098,0.0001120744,0.00009945747,0.0002490185,0.0008984134,0.004188033,0.1284154,0.8165748],"study_design_scores_gemma":[0.0001029517,0.0001129342,0.0006297876,0.02231152,0.0004121067,0.0002662725,0.0001027524,0.00006547937,0.000144143,0.001749694,0.9740771,0.00002516021],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001691699,0.9984202,0.00003412822,0.0007970798,0.0005288942,0.000003758139,0.00001428636,0.000005164727,0.0001795077],"genre_scores_gemma":[0.0001955855,0.9978743,0.0001507981,0.001073255,0.0004998088,0.000008079908,0.00003367544,0.000001570017,0.0001629678],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006467747,"threshold_uncertainty_score":0.03420514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3252617865824189,"score_gpt":0.4958881625737818,"score_spread":0.1706263759913629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}