{"id":"W4324056768","doi":"10.3390/cells12060883","title":"Environmental Enrichment Engages Vesicular Zinc Signaling to Enhance Hippocampal Neurogenesis","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Calgary; University of Washington","keywords":"Neurogenesis; Hippocampal formation; Dentate gyrus; Hippocampus; Neuroscience; Synaptic plasticity; Biology; Neuroplasticity; Environmental enrichment; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007369887,0.0002658987,0.000362475,0.000163389,0.0001247811,0.0002699433,0.0001981099,0.0002298411,0.0007519248],"category_scores_gemma":[0.0001046223,0.0001384286,0.0002390362,0.00009948088,0.0003024678,0.000189105,0.0004739033,0.0003771477,0.0001112554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002590125,"about_ca_system_score_gemma":0.000193543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009421096,"about_ca_topic_score_gemma":0.003301275,"domain_scores_codex":[0.999894,0.00001029067,0.000008823808,0.00002125464,0.00002148075,0.00004420369],"domain_scores_gemma":[0.9999182,0.00001078663,0.00002676755,0.000007585209,0.000005874804,0.00003076416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000342113,0.00001963438,0.00049853,0.00003866222,0.000006102742,0.00007332092,0.00001544486,0.00004103853,0.9976974,0.00004729794,0.00001587675,0.001204653],"study_design_scores_gemma":[0.00004091102,0.0004964503,0.02932924,0.00001434729,0.00003531944,0.0002430134,0.00007790514,0.0006080761,0.9678584,0.0001059117,0.001181344,0.000009034573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981009,0.0004304155,0.0009342091,0.00003764751,0.000006910751,0.000007109059,0.0001097383,0.0000303469,0.000342682],"genre_scores_gemma":[0.9975201,0.000397484,0.001139672,0.00002446519,0.000003717588,0.00001788441,0.00009442095,0.00001195905,0.0007903093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009421096,"threshold_uncertainty_score":0.002515376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02314673089248329,"score_gpt":0.2572565133907657,"score_spread":0.2341097824982824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}