{"id":"W4324135698","doi":"10.1016/j.semcancer.2023.03.004","title":"Role of E2F transcription factor in oral cancer: Recent insight and advancements","year":2023,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Qatar National Library; Qatar National Research Fund; Qatar University","keywords":"E2F; Biology; E2F1; Cell cycle; Cancer research; Transcription factor; Epigenetics; Cancer; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001812075,0.0004164227,0.002044293,0.0006497289,0.00001708996,0.000003472247,0.000152693,0.0007116143,0.0001759573],"category_scores_gemma":[0.00005572937,0.0003697103,0.000163351,0.0009339653,0.0001565585,0.00003559427,0.00007381137,0.0006983172,0.000005619836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001230878,"about_ca_system_score_gemma":0.0008127209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001648189,"about_ca_topic_score_gemma":0.005102266,"domain_scores_codex":[0.9976245,0.0001836127,0.0009055466,0.0006846894,0.0001517993,0.0004498205],"domain_scores_gemma":[0.9991044,0.00006932182,0.0003514808,0.0003170847,0.00006208685,0.00009559537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001143385,0.00007461722,0.001087033,0.005964689,0.0001593169,0.00002608078,0.0003433542,0.000004375754,0.002632565,0.00001941887,0.00008403373,0.9894902],"study_design_scores_gemma":[0.001265667,0.0003372763,0.0002419157,0.03338655,0.000316485,0.00001747493,0.00004594086,0.000009839015,0.000385452,0.00007719333,0.9636185,0.0002976949],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003000862,0.9937987,0.000003720525,0.00008071816,0.0009013891,0.001447845,0.0005734325,0.00002998951,0.0001633426],"genre_scores_gemma":[0.0003654118,0.9980664,0.00007912534,0.00006099494,0.00009460541,0.0008042006,0.0003172779,0.0000796198,0.0001324241],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9891925,"threshold_uncertainty_score":0.9998755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07075524022119532,"score_gpt":0.3951314308656401,"score_spread":0.3243761906444448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}