{"id":"W4324140519","doi":"10.1161/circ.147.suppl_1.65","title":"Abstract 65: DNA Methylation at <i>ABCG1</i> and Long-Term Changes in Adiposity in Response to Diet Interventions: The POUNDS Lost Trial","year":2023,"lang":"en","type":"article","venue":"Circulation","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"dNaM; Medicine; Adipose tissue; Waist; Overweight; Internal medicine; Endocrinology; Obesity; Weight loss; DNA methylation; Body mass index; Physiology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001637232,0.0006856269,0.001917697,0.0002335343,0.0003795747,0.00097097,0.000441831,0.001133403,0.004174201],"category_scores_gemma":[0.001360131,0.0002736883,0.001762414,0.0003122164,0.0006068583,0.0006436954,0.0004417923,0.001746595,0.000560254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003489793,"about_ca_system_score_gemma":0.0004466627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001011602,"about_ca_topic_score_gemma":0.0009580262,"domain_scores_codex":[0.9994277,0.0002959998,0.00004951641,0.0001050266,0.00005843179,0.00006324735],"domain_scores_gemma":[0.9995353,0.00009932551,0.0001408474,0.00005878968,0.00004172834,0.000123982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.91958,0.003680762,0.02394181,0.001918503,0.008867548,0.00008666296,0.0001104223,0.0004576965,0.004958122,0.0002349813,0.002700422,0.03346309],"study_design_scores_gemma":[0.7017803,0.1371043,0.1315328,0.0007852006,0.01648442,0.000199542,0.0001753513,0.001736115,0.002854223,0.001337717,0.005944727,0.00006532297],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847342,0.008516731,0.0007228056,0.0013011,0.0003304007,0.0007731311,0.001456092,0.00007171659,0.002093747],"genre_scores_gemma":[0.9906261,0.001515532,0.0005993685,0.001266664,0.0002786128,0.001386675,0.001293997,0.00001800417,0.003015155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004174201,"threshold_uncertainty_score":0.01396412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0405731820925837,"score_gpt":0.3236481279930618,"score_spread":0.283074945900478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}