{"id":"W4324141754","doi":"10.1016/j.joca.2023.01.512","title":"Cartilage Specific Transforming Growth Factor Beta Receptor II Deletion Drives Medial Collateral Ligament Calcification In Spontaneous Mouse OA","year":2023,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Medial collateral ligament; Calcification; Cartilage; Transforming growth factor beta; Anatomy; Medicine; Receptor; Ligament; Pathology; Chemistry; Cell biology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007808998,0.001350841,0.0008416356,0.002787221,0.0007148277,0.001376843,0.0009858368,0.001772079,0.005589782],"category_scores_gemma":[0.0006531872,0.001270526,0.0009374652,0.0008535063,0.001583772,0.0006009022,0.0008668231,0.002367215,0.002238946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005962941,"about_ca_system_score_gemma":0.0004851024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001504802,"about_ca_topic_score_gemma":0.002939246,"domain_scores_codex":[0.9985443,0.0002397225,0.0002302348,0.0002675254,0.0004206382,0.0002975257],"domain_scores_gemma":[0.9970173,0.0004841422,0.001410017,0.0002877798,0.0001279108,0.0006730369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000247597,0.0001260676,0.000232003,0.00003273144,0.000008936706,0.0003708255,0.00003752682,0.00006892075,0.9981324,0.0002992465,0.00004392714,0.0003998906],"study_design_scores_gemma":[0.0003312053,0.0007190334,0.006959321,0.00003493726,0.00009023599,0.003359104,0.0002778365,0.00201391,0.9829134,0.0002543705,0.003011484,0.00003513547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894749,0.001174535,0.004758882,0.0002446067,0.00009446533,0.0001071749,0.001130432,0.0005825124,0.002432493],"genre_scores_gemma":[0.9826706,0.0007086487,0.002963556,0.0001458772,0.00006585714,0.0001550106,0.000767034,0.0004320988,0.01209132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005589782,"threshold_uncertainty_score":0.01869971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246152417013292,"score_gpt":0.2493847047980187,"score_spread":0.2369231806278858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}