{"id":"W4324357321","doi":"10.3390/biomedicines11030898","title":"Identification and Elimination of Antifungal Tolerance in Candida auris","year":2023,"lang":"en","type":"article","venue":"Biomedicines","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Science Education Institute, Department of Science and Technology, Republic of the Philippines; Government of Canada; Alberta Precision Laboratories; University of Alberta; Government of Alberta","keywords":"Candida auris; Fluconazole; Echinocandin; Antifungal drug; Biology; Microbiology; Fungal pathogen; Antifungal drugs; Drug resistance; Antifungal; Multiple drug resistance; Cryptococcus neoformans; Pathogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001092827,0.0001768092,0.0002858636,0.0005458955,0.0002336045,0.0004507943,0.0001738381,0.0002379164,0.0004770187],"category_scores_gemma":[0.0002553972,0.00009648375,0.0002091304,0.000384206,0.0001538277,0.0001500728,0.0002953041,0.0002495835,0.0001605228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001587007,"about_ca_system_score_gemma":0.0001651385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002398743,"about_ca_topic_score_gemma":0.001678923,"domain_scores_codex":[0.999831,0.0000217674,0.00002296085,0.00003263547,0.00006021393,0.00003146038],"domain_scores_gemma":[0.9998177,0.00002393829,0.00005804938,0.0000219502,0.00004985621,0.00002862673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001676823,0.00002905674,0.005667351,0.00003348878,0.00000494685,0.0001420951,0.00005090127,0.00003741531,0.989863,0.00003292874,0.00003086338,0.003940208],"study_design_scores_gemma":[0.00001227252,0.000951271,0.2690187,0.0000208206,0.00003851581,0.00275438,0.0003378837,0.001559079,0.7226986,0.0001190271,0.002467473,0.00002211869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974904,0.0007972824,0.0006691889,0.00003275612,0.000008413174,0.00001626427,0.0002308979,0.00002325066,0.0007315113],"genre_scores_gemma":[0.997871,0.0003400682,0.000810185,0.0000339892,0.000006547003,0.00001442651,0.0003248096,0.000005096876,0.0005938695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002398743,"threshold_uncertainty_score":0.004769564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01616404866205149,"score_gpt":0.3033972268044282,"score_spread":0.2872331781423767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}