{"id":"W4324357321","doi":"10.3390/biomedicines11030898","title":"Identification and Elimination of Antifungal Tolerance in Candida auris","year":2023,"lang":"en","type":"article","venue":"Biomedicines","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Science Education Institute, Department of Science and Technology, Republic of the Philippines; Government of Canada; Alberta Precision Laboratories; University of Alberta; Government of Alberta","keywords":"Candida auris; Fluconazole; Echinocandin; Antifungal drug; Biology; Microbiology; Fungal pathogen; Antifungal drugs; Drug resistance; Antifungal; Multiple drug resistance; Cryptococcus neoformans; Pathogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003616038,0.00006352795,0.0001920251,0.0002571274,0.00002264245,0.000003591928,0.00003108184,0.000050169,0.00001948093],"category_scores_gemma":[0.00020292,0.00005167153,0.00002145208,0.0006615634,0.0001397857,0.00005585293,0.00001251312,0.00004823248,0.0000100186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002115717,"about_ca_system_score_gemma":0.00003738359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00011855,"about_ca_topic_score_gemma":0.00007252733,"domain_scores_codex":[0.9992287,0.00001729536,0.0002705004,0.0001731124,0.0001960851,0.0001143229],"domain_scores_gemma":[0.9996085,0.00005298811,0.00006278802,0.0001488049,0.00008425332,0.00004272904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001277238,0.00005048092,0.6629424,0.0003806243,0.000007606478,0.00002042229,0.0005194728,6.785909e-7,0.3230607,0.0001173285,0.001664411,0.01110814],"study_design_scores_gemma":[0.0006075331,0.00007863767,0.9878316,0.000184181,0.00001679107,0.000004594409,0.0004937796,0.0007005925,0.009564006,0.00009559296,0.0003793935,0.0000432872],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973658,0.0005021921,0.00005872518,0.001476883,0.0001321306,0.0001837303,0.00000777253,0.00003308542,0.0002396708],"genre_scores_gemma":[0.9983786,0.000432573,0.00003049698,0.00004389347,0.00006928773,0.000007595106,0.00003477214,0.00000577863,0.000997043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3248892,"threshold_uncertainty_score":0.2107104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01616404866205149,"score_gpt":0.3033972268044282,"score_spread":0.2872331781423767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}