{"id":"W4327520342","doi":"10.7554/elife.84051.sa2","title":"Author response: Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis","year":2022,"lang":"en","type":"peer-review","venue":"","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"","keywords":"Mendelian randomization; Alcohol consumption; Mendelian inheritance; Consumption (sociology); Randomization; Medicine; Alcohol; Environmental health; Genetics; Biology; Internal medicine; Randomized controlled trial; Gene; Sociology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01167876,0.0009752431,0.001964395,0.001295374,0.001396801,0.00157677,0.001572989,0.009124408,0.1489966],"category_scores_gemma":[0.1603509,0.0007776416,0.001999176,0.001336964,0.000983804,0.00128034,0.0013409,0.005100167,0.04284282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001915821,"about_ca_system_score_gemma":0.003556209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003459417,"about_ca_topic_score_gemma":0.003180462,"domain_scores_codex":[0.9888832,0.006720612,0.00115601,0.000859016,0.001817408,0.0005637573],"domain_scores_gemma":[0.9348926,0.04205548,0.003578294,0.002430086,0.01502764,0.00201597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003234266,0.00001910046,0.0007600953,0.0003005341,0.00006233607,0.00005482551,0.00002561302,0.00005718005,0.00002072293,0.0003538488,0.9923427,0.005679592],"study_design_scores_gemma":[0.005005788,0.0005985496,0.01419255,0.004281459,0.0006182084,0.001039174,0.0008007757,0.001267165,0.0004280771,0.00906554,0.9624387,0.0002639161],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.002613122,0.002532807,0.002168002,0.7901256,0.1717749,0.0009556061,0.01262816,0.001081378,0.01612036],"genre_scores_gemma":[0.03223344,0.003293786,0.003174067,0.8450693,0.0473313,0.004477112,0.004578716,0.000628818,0.05921353],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.1489966,"threshold_uncertainty_score":0.4984432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1234115189315642,"score_gpt":0.4264228672903771,"score_spread":0.303011348358813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}