{"id":"W4327546647","doi":"10.1016/j.repbio.2023.100755","title":"Suitability of a universal electroporation device for genome editing and production of transgenic rats","year":2023,"lang":"en","type":"article","venue":"Reproductive Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Razi Vaccine and Serum Research Institute; Iran National Science Foundation","keywords":"mCherry; Electroporation; Genome editing; Zygote; Transgenesis; Biology; Green fluorescent protein; CRISPR; Embryo; Transgene; Cas9; Reporter gene; Reproductive technology; Blastocyst; Molecular biology; Cell biology; Gene; Genetics; Gene expression; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009049019,0.0003927842,0.0003714768,0.0003644061,0.0002201766,0.000428767,0.0005248924,0.0006062802,0.001417993],"category_scores_gemma":[0.0006852823,0.0003030133,0.0003945687,0.0001878714,0.0004351495,0.0004535816,0.0005624882,0.0005653613,0.0007285036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001638925,"about_ca_system_score_gemma":0.0003241184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002544966,"about_ca_topic_score_gemma":0.0004035327,"domain_scores_codex":[0.9992443,0.0001239748,0.0001047886,0.0002306648,0.0001515262,0.0001447211],"domain_scores_gemma":[0.9994699,0.0001764146,0.000128379,0.0001135798,0.00004805754,0.00006369675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004716941,0.00001078319,0.0001139889,0.0000227497,0.000002096573,0.00004465995,0.00001583398,0.00004995085,0.9975305,0.0002182329,0.00002689529,0.001917025],"study_design_scores_gemma":[0.00001181636,0.0001853169,0.001357384,0.000008986395,0.00001738784,0.0006124626,0.00001980278,0.0006668274,0.9939075,0.00007679822,0.00312428,0.0000112766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7047339,0.0008525356,0.2884968,0.0004060736,0.00020263,0.0003919615,0.0008416075,0.001148898,0.00292562],"genre_scores_gemma":[0.7891057,0.00119917,0.1996049,0.0001715153,0.00004027368,0.0005404922,0.001400524,0.0004772252,0.007460251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001417993,"threshold_uncertainty_score":0.004785657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374524064073698,"score_gpt":0.3186320280190305,"score_spread":0.3048867873782935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}