{"id":"W4327546647","doi":"10.1016/j.repbio.2023.100755","title":"Suitability of a universal electroporation device for genome editing and production of transgenic rats","year":2023,"lang":"en","type":"article","venue":"Reproductive Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Razi Vaccine and Serum Research Institute; Iran National Science Foundation","keywords":"mCherry; Electroporation; Genome editing; Zygote; Transgenesis; Biology; Green fluorescent protein; CRISPR; Embryo; Transgene; Cas9; Reporter gene; Reproductive technology; Blastocyst; Molecular biology; Cell biology; Gene; Genetics; Gene expression; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000357602,0.00006847378,0.0001253104,0.00004864876,0.00002548486,0.000001009199,0.00004269208,0.00006947134,0.000001093646],"category_scores_gemma":[0.0002898026,0.00006887352,0.00003884271,0.0001308877,0.00008895883,0.000002834581,0.00002303476,0.00002860262,1.844312e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007718033,"about_ca_system_score_gemma":0.00003081734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009007686,"about_ca_topic_score_gemma":0.00001313787,"domain_scores_codex":[0.9993007,0.0000360653,0.0001545199,0.0003611514,0.00002638398,0.0001212033],"domain_scores_gemma":[0.9995573,0.00001211115,0.00007002972,0.0001938335,0.0001512307,0.00001548729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009304371,0.00001463934,0.001946119,0.00007663153,0.00003821185,3.461489e-8,0.000148772,0.0002180817,0.9958784,0.0001231619,0.00002462927,0.001438299],"study_design_scores_gemma":[0.0001481687,0.0004118312,0.01130703,0.000002547742,0.00001853222,0.00000259005,0.0002202452,0.00003822614,0.9860175,0.0002999026,0.001469601,0.00006386611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942343,0.0005649707,0.004535214,0.0001802112,0.0001418562,0.000297291,0.00001961179,0.00001036026,0.0000162058],"genre_scores_gemma":[0.9987002,0.0001562618,0.0005646744,0.000002078079,0.0003312161,0.00001530128,0.0001705418,0.000008113729,0.00005161445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009860918,"threshold_uncertainty_score":0.280858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374524064073698,"score_gpt":0.3186320280190305,"score_spread":0.3048867873782935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}