{"id":"W4327564973","doi":"10.1021/acsomega.2c07762","title":"Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting","year":2023,"lang":"en","type":"article","venue":"ACS Omega","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Lundbeckfonden","keywords":"Aptamer; In vivo; Nanocarriers; Nanoprobe; Chemistry; Biophysics; Cancer research; Nanotechnology; Materials science; Molecular biology; Biology; Drug delivery; Nanoparticle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003775967,0.0003629678,0.0001618458,0.0002108589,0.0000946712,0.0001893596,0.000196842,0.0004061886,0.0006750968],"category_scores_gemma":[0.0003869826,0.0001217017,0.0001172638,0.0002162585,0.0002251206,0.0002049115,0.0001315136,0.0002961411,0.0001883826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003212344,"about_ca_system_score_gemma":0.0002340675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004619591,"about_ca_topic_score_gemma":0.0006446025,"domain_scores_codex":[0.9997906,0.00003986057,0.00001165734,0.00005600405,0.0000751047,0.00002675485],"domain_scores_gemma":[0.9997723,0.00006978595,0.00005774164,0.0000167308,0.00005428766,0.00002921221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003080996,0.00001002048,0.00009045679,0.00001672129,0.000002067421,0.000009661504,0.00001428315,0.0001056312,0.9988355,0.00002221861,0.000009044276,0.0008535327],"study_design_scores_gemma":[0.00000384927,0.0001956579,0.0007785011,0.000001731022,0.000008527861,0.00003592035,0.00000610131,0.003602698,0.9950728,0.00001055169,0.0002811887,0.000002528926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748585,0.0009343502,0.02279681,0.0000557151,0.00001778121,0.00008154549,0.0001315855,0.0001657186,0.0009579459],"genre_scores_gemma":[0.9748021,0.0005182615,0.02266949,0.00003643521,0.000006024404,0.0001084639,0.0002024297,0.00003271517,0.001624116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006750968,"threshold_uncertainty_score":0.00233078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03397331014369831,"score_gpt":0.3491774504507839,"score_spread":0.3152041403070856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}