{"id":"W4327568981","doi":"10.1038/s41590-023-01468-3","title":"MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation","year":2023,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture; Fonds Wetenschappelijk Onderzoek; Walloon excellence in life sciences and biotechnology; China Scholarship Council; Fonds De La Recherche Scientifique - FNRS; Fédération Wallonie-Bruxelles; Wallonie-Bruxelles International; Fondation Acteria","keywords":"Biology; Cell biology; Monocyte; Progenitor cell; Immunology; Macrophage; Cellular differentiation; Bone marrow; Mononuclear phagocyte system; Stem cell; Gene; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001261438,0.0001860018,0.0002506772,0.0002827319,0.0001116055,0.0003293112,0.0001014397,0.000228302,0.00102441],"category_scores_gemma":[0.0001147472,0.0001276797,0.0001871605,0.000113598,0.0002008819,0.0001181704,0.0001916552,0.0006699717,0.0005021464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002326589,"about_ca_system_score_gemma":0.0001790059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001119402,"about_ca_topic_score_gemma":0.001228052,"domain_scores_codex":[0.9998515,0.00001935817,0.000009688354,0.00003735423,0.00002784606,0.00005420065],"domain_scores_gemma":[0.9997852,0.00004756187,0.00004843648,0.00002626611,0.00002930602,0.00006325091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006399837,0.00000732176,0.0004671022,0.00001435312,0.000001000703,0.00003684919,0.00001489569,0.0000188856,0.9985558,0.0000778481,0.00001732055,0.0007245612],"study_design_scores_gemma":[0.000005899229,0.0002286151,0.01851373,0.0000104616,0.000006335785,0.0002233833,0.00005899114,0.0005413003,0.9787492,0.00004588359,0.001612684,0.000003419312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886757,0.002544058,0.005129945,0.00006171404,0.00001974681,0.00002641666,0.0005029785,0.0001772129,0.002862073],"genre_scores_gemma":[0.9951332,0.000383331,0.001364521,0.00004107556,0.00001138651,0.00002795206,0.0002815522,0.00002094134,0.002735985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001119402,"threshold_uncertainty_score":0.003427029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005883769368385208,"score_gpt":0.2537424807317699,"score_spread":0.2478587113633847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}