{"id":"W4327675508","doi":"10.1093/nar/gkad187","title":"Short tandem repeats are important contributors to silencer elements in T cells","year":2023,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Fondation Bettencourt Schueller; Canceropôle PACA; CNIB; Government of Alberta; Aix-Marseille Université","keywords":"Silencer; Biology; Psychological repression; Chromatin; Enhancer; Gene; Genetics; Repressor; Regulation of gene expression; Promoter; Transcription factor; Reporter gene; Transcription (linguistics); Regulatory sequence; Gene expression; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002928045,0.0003314764,0.000373372,0.0004511453,0.000238004,0.0005213713,0.0002881882,0.000550993,0.001369492],"category_scores_gemma":[0.0004495836,0.000233245,0.0003665817,0.0003715646,0.0003470396,0.0002811803,0.0003248989,0.0005077791,0.001097052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002699194,"about_ca_system_score_gemma":0.0002112693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004146393,"about_ca_topic_score_gemma":0.0007359038,"domain_scores_codex":[0.9995876,0.00005394782,0.00003196214,0.0001355357,0.0001543097,0.00003672882],"domain_scores_gemma":[0.9996738,0.00006525206,0.000140689,0.00003617265,0.00003851105,0.00004555176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003626954,0.000003907498,0.0005071716,0.00003808079,0.000008662289,0.00004804374,0.00001963299,0.0001012537,0.9970355,0.000158857,0.00002301212,0.002019582],"study_design_scores_gemma":[0.00001219509,0.0002740946,0.01369989,0.00001871798,0.00006844397,0.001048166,0.00007702829,0.002443785,0.973755,0.000980883,0.007602496,0.00001933039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8903798,0.01309707,0.08885209,0.0003295678,0.00009722639,0.00008642027,0.001761072,0.0009502383,0.004446506],"genre_scores_gemma":[0.9768295,0.001813167,0.01580964,0.0002044103,0.00004534696,0.0000485649,0.00142482,0.0001517738,0.003672862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001369492,"threshold_uncertainty_score":0.004581451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02862282199972107,"score_gpt":0.335000836132245,"score_spread":0.3063780141325239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}