{"id":"W4327811353","doi":"10.1111/cts.13514","title":"Pharmacokinetics of intranasal amiloride in healthy volunteers","year":2023,"lang":"en","type":"article","venue":"Clinical and Translational Science","topic":"Olfactory and Sensory Function Studies","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Centre of Excellence for Child and Youth Mental Health; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Nasal administration; Amiloride; Medicine; Pharmacology; Pharmacokinetics; Anxiety; Psychiatry; Sodium; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004899351,0.0004026289,0.0005392606,0.0001688516,0.0002682863,0.0003512666,0.0001281577,0.0004474579,0.001494578],"category_scores_gemma":[0.0008306998,0.0002646536,0.0001934982,0.0001319472,0.0002795796,0.0002891873,0.0001589443,0.0005134242,0.0007333754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000149711,"about_ca_system_score_gemma":0.0003153476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008712449,"about_ca_topic_score_gemma":0.0007022273,"domain_scores_codex":[0.9997,0.00009033205,0.00001826989,0.00009122957,0.00006698129,0.00003332239],"domain_scores_gemma":[0.9997426,0.00006522898,0.00004925808,0.0000322938,0.00004530737,0.00006542853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.107065,0.009079197,0.03277091,0.0003969331,0.0003394592,0.001198066,0.001177211,0.0009291202,0.7250459,0.0002487357,0.003125456,0.1186241],"study_design_scores_gemma":[0.008191806,0.4617616,0.3706028,0.00007044018,0.0006361715,0.005089824,0.0009782433,0.01004494,0.1282982,0.0006328893,0.01355848,0.0001348108],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933656,0.001218971,0.002274485,0.00006766919,0.00005379285,0.0005489812,0.0004755178,0.0001371835,0.00185779],"genre_scores_gemma":[0.9941466,0.0005989641,0.001918471,0.0002593177,0.00005693961,0.0003887201,0.000483266,0.00002364951,0.00212407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001494578,"threshold_uncertainty_score":0.004999876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2998012662352414,"score_gpt":0.4139924891989067,"score_spread":0.1141912229636653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}