{"id":"W4327862357","doi":"10.1101/2023.03.17.532992","title":"BCL7 proteins, metazoan-specific subunits of the mammalian SWI/SNF complex, bind the nucleosome core particle","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Université de Strasbourg; Fondation pour la Recherche Médicale","keywords":"Nucleosome; SWI/SNF; Chromatin; DNA-binding protein; Mutation; Biology; DNA; Function (biology); Chromatin remodeling; Protein subunit; Cell biology; Chemistry; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001018431,0.0002306065,0.0001408697,0.0003173611,0.000255311,0.0003038099,0.0001667827,0.0003132405,0.005210023],"category_scores_gemma":[0.0001863561,0.0001084546,0.0001495154,0.0001777134,0.0002176895,0.0001438094,0.0002606592,0.0002814904,0.002364759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002627439,"about_ca_system_score_gemma":0.0001241548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009291432,"about_ca_topic_score_gemma":0.001223678,"domain_scores_codex":[0.9998975,0.00001368621,0.000004300158,0.00001844206,0.00004778172,0.00001830664],"domain_scores_gemma":[0.9999207,0.00002033737,0.00001614851,0.00001015802,0.0000133825,0.00001935637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001056826,0.00001717413,0.003208246,0.00006978839,0.00001737604,0.0002026521,0.00002988186,0.0001009884,0.9906114,0.0007068707,0.0006286667,0.004301314],"study_design_scores_gemma":[0.00001995865,0.00005884247,0.01830198,0.00001330243,0.0000143276,0.0009142285,0.00005970781,0.001790162,0.9628082,0.0004767557,0.01553827,0.000004307408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703037,0.004174262,0.01154253,0.0003550136,0.00008742893,0.00003336367,0.00148375,0.0003803671,0.01163952],"genre_scores_gemma":[0.9742193,0.0009255452,0.006356,0.00009146671,0.00002170168,0.0000197696,0.004355783,0.00009153844,0.01391878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005210023,"threshold_uncertainty_score":0.01742923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04595113893657208,"score_gpt":0.245172089311374,"score_spread":0.1992209503748019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}