{"id":"W4327900107","doi":"10.1371/journal.pone.0283286","title":"A critical role for ecdysone response genes in regulating egg production in adult female Rhodnius prolixus","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene knockdown; Biology; Rhodnius prolixus; Ecdysone; RNA interference; Hemolymph; Vitellogenin; Ecdysone receptor; Gene expression; Vitellogenesis; Blood meal; Internal medicine; Gene; Endocrinology; Cell biology; Transcription factor; RNA; Nuclear receptor; Genetics; Insect; Medicine; Oocyte","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004218924,0.0002666794,0.0001617665,0.0002379475,0.0001630531,0.000228581,0.0001420553,0.0002153971,0.0005115779],"category_scores_gemma":[0.0000857262,0.0001697181,0.0001812435,0.00006574084,0.0002366874,0.0001598907,0.0002440487,0.0002934615,0.0002114629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003581588,"about_ca_system_score_gemma":0.0001855825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003618051,"about_ca_topic_score_gemma":0.005920898,"domain_scores_codex":[0.9999348,0.00000425575,0.000004385093,0.00002797114,0.000012714,0.00001575982],"domain_scores_gemma":[0.9999149,0.000008760485,0.00002795176,0.000005314699,0.00001405631,0.00002911988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002626088,0.000002888561,0.0006158753,0.00001306911,0.000001240713,0.00004012235,0.00001241436,0.00001670191,0.9986477,0.00002407071,0.000009863368,0.0005898239],"study_design_scores_gemma":[0.0000262884,0.000323564,0.4157378,0.00002472543,0.0000295151,0.0005131015,0.0002459277,0.001117573,0.5789655,0.00008383905,0.002913452,0.0000186481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954828,0.0009630172,0.001136581,0.00008862234,0.000007601412,0.00001561145,0.0004960264,0.00004278986,0.001767055],"genre_scores_gemma":[0.991354,0.0004063264,0.00193109,0.0001194167,0.000005437616,0.00002609378,0.0007369572,0.00002685321,0.005393801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003618051,"threshold_uncertainty_score":0.007193983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1103255952579414,"score_gpt":0.3413965785556211,"score_spread":0.2310709832976797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}