{"id":"W4327915029","doi":"10.1212/wnl.0000000000207079","title":"Pearls &amp; Oy-sters: Homozygous Complement Factor I Deficiency Presenting as Fulminant Relapsing Complement-Mediated CNS Vasculitis","year":2023,"lang":"en","type":"article","venue":"Neurology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Complement factor B; Fulminant; Alternative complement pathway; Factor H; Complement system; Vasculitis; Medicine; Complement factor I; Immunology; Pathology; Disease; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001790194,0.001595343,0.0006654774,0.001375996,0.001073297,0.0006618034,0.0007232595,0.001857839,0.003047605],"category_scores_gemma":[0.001532974,0.0004097172,0.0003736556,0.0006939513,0.001036153,0.0008826059,0.0006667849,0.001189811,0.0007142782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006518491,"about_ca_system_score_gemma":0.000564864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00212064,"about_ca_topic_score_gemma":0.002077472,"domain_scores_codex":[0.9997855,0.00001687076,0.00001923177,0.00007039301,0.00004511773,0.00006289531],"domain_scores_gemma":[0.9994797,0.0001293065,0.0001232105,0.00003584673,0.0000395789,0.000192389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00003572517,0.00002234153,0.003077914,0.00002536243,0.00000630098,0.9940028,0.00006316855,0.00003421462,0.0006804659,0.0001585314,0.0005281552,0.001365106],"study_design_scores_gemma":[0.00002036171,0.0001351158,0.009850531,0.00002599625,0.00001411058,0.9870844,0.00009657996,0.0002701921,0.0007698931,0.0004017313,0.001317735,0.00001332538],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.958627,0.004024702,0.002344523,0.005222199,0.0005740101,0.0002468033,0.0006156461,0.0003307633,0.02801437],"genre_scores_gemma":[0.9946499,0.0008190818,0.0005478546,0.0007065042,0.0002033194,0.00001385255,0.00009760497,0.00002500438,0.00293679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003047605,"threshold_uncertainty_score":0.01019531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04632903497686983,"score_gpt":0.2948887052974011,"score_spread":0.2485596703205313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}